Predictive factors for new onset or progression of knee osteoarthritis one year after trauma: MRI follow-up in general practice
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Ingrid M. Koster & Edwin H. G. Oei & Jan-Hein J. Hensen & Simone S. Boks & Bart W. Koes & Dammis Vroegindeweij & M. G. Myriam Hunink & Sita M. A. Bi
- چاپ و سال / کشور: 2011
Description
Objective To prospectively evaluate prognostic factors for new onset or progression of degenerative change on followup MRI one year after knee trauma and the association with clinical outcome. Methods Within a prospective observational cohort study in general practice, we studied a subgroup of 117 patients with acute knee trauma (mean age 41 years, 43% women). Degenerative change was scored on MRI at baseline and after one year follow-up. Multivariate logistic regressionanalysis was performed to evaluate prognostic factors for new onset or progressive degenerative change on follow-up MRI. Association between new or progressive degeneration and clinical outcome after one year was assessed. Results On follow-up MRI 15% of patients with pre-existing knee osteoarthritis showed progression and 26% of patients demonstrated new degenerative change. The only statistically significant prognostic variable in the multivariate analysis was bone marrow oedema on initialMRI (OR 5.29 (95%CI 1.64– 17.1), p=0.005). A significant association between new or progressive degenerative change and clinical outcome was found (p=0.003). Conclusion Bone marrow oedema on MRI for acute knee injury is strongly predictive of new onset or progression of degenerative change of the femorotibial joint on follow-up MRI one year after trauma, which is reflected in clinical outcome.
Eur Radiol (2011) 21:1509–1516 DOI 10.1007/s00330-011-2089-3 Received: 14 October 2010 / Revised: 19 December 2010 / Accepted: 16 January 2011 / Published online: 6 March 2011
