ECG-Triggered Non-Contrast-Enhanced MR Angiography (TRANCE) versus Digital Subtraction Angiography (DSA) in patients with peripheral arterial occlusive disease of the lower extremities
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Andreas Gutzeit & Reto Sutter & Johannes M. Froehlich & Justus E. Roos & Thomas Sautter & Erik Schoch & Barbara Giger &Michael Wyss & Nicole Graf &
- چاپ و سال / کشور: 2011
Description
Objective To prospectively determine the diagnostic value of electrocardiography-triggered non-contrast-enhanced magnetic resonance angiography (TRANCE) of the lower extremities including the feet versus DSA. Methods All 43 patients with symptomatic peripheral arterial occlusive disease (PAOD) underwent TRANCE before DSA. Quality of MRA vessel depiction was rated by two independent radiologists on a 3-point scale. Arterial segments were graded for stenoses using a 4-point scale (grade 1: no stenosis; grade 2: moderate stenosis; grade 3: severe stenosis; grade 4: occlusion). Findings were compared with those of DSA. Results In the 731 vessel segments analysed, intra-arterial DSA revealed 283 stenoses: 33.6% moderate, 16.6% severe and 49.8% occlusions. TRANCE yielded a mean sensitivity, specificity, positive and negative predictive value and diagnostic accuracy to detect severe stenoses or occlusions of 95.6%, 97.4%, 87.2%, 99.2%, 97.1% for the thigh segments and 95.2%, 87.5%, 83.2%, 96.6%, 90.5% for the calf segments. Excellent overall image quality was observed for TRANCE in 91.4% versus 95.7% (DSA) for the thigh and in 60.7%versus 91.0%for the calves, while diagnostic quality of the pedal arteries was rated as insufficient. Conclusion TRANCE achieves high diagnostic accuracy in the thigh and calf regions, whereas the pedal arteries showed limited quality.
Eur Radiol (2011) 21:1979–1987 DOI 10.1007/s00330-011-2132-4 Received: 1 February 2011 / Revised: 18 March 2011 / Accepted: 27 March 2011 / Published online: 1 May 2011
