Nonenhanced ECG-gated time-resolved 4D Steady-state free precession (SSFP) MR angiography (MRA) for assessment of cerebral collateral flow: comparison with digital subtraction angiography (DSA)
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Rotem Shlomo Lanzman & Patric Krِpil & Peter Schmitt & Xiaoming Bi & Michael Gliem & Falk R. Miese & Daniel Hنnggi & Marcel Kamp & Axel Scherer & Be
- چاپ و سال / کشور: 2011
Description
Objectives To evaluate a nonenhanced time-resolved 4D SSFP MRA for dynamic visualization of intracranial collateral blood flow. Methods 22 patients (59.0±11.8 years) with steno-occlusive disease of brain-supplying arteries were included in this study. 4D SSFP MRA of the intracranial arteries was acquired with 15 temporal phases and a temporal resolution of 115 ms using 1.5 T MR. Cerebral DSA served as the reference standard and was available in all patients. Results Nonenhanced 4D SSFP MRA allowed for detailed dynamic visualization of blood flow in the circle of Willis and its branches in 21 of 22 (95.5%) patients. Collateral flow was excluded with both 4D SSFP MRA and DSA in 4 patients. In 17 patients, DSA detected anterior collateral flow (n=8), posterior collateral flow via the right (n=8) and left (n=7) posterior communicating artery as well as patent EC-IC bypasses (n=8). 29 of 31 collateral flow pathways were visualized by 4D SSFP MRA. As compared to DSA, 4D SSFP MRA showed a high sensitivity (92.3%), specificity (100%), positive predictive value (100%) and negative predictive value (95.2%) for visualization of intracranial collateral flow. Conclusions 4D SSFP MRA is a promising non-invasive imaging technique for dynamic visualization of intracranial collateral flow.
Eur Radiol (2011) 21:1329–1338 DOI 10.1007/s00330-010-2051-9 Received: 12 September 2010 / Revised: 6 November 2010 / Accepted: 12 November 2010 / Published online: 12 January 2011
