Radio-opaque ethylcellulose-ethanol is a safe and efficient sclerosing agent for venous malformations
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Anne Dompmartin & Xavier Blaizot & Jacques Théron & Frank Hammer & Yannick Chene & Daniel Labbé & Marie-Thérèse Barrellier & Cathy Gaillard & Robert
- چاپ و سال / کشور: 2011
Description
Objective To evaluate the efficacy and safety of gelified ethanol, a newly developed sclerosing agent for slow-flow vascular malformations. Methods Seventy-nine sclerotherapy procedures were performed on 44 patients with 37 venous malformations, 2 glomuvenous malformations, 2 lymphatic malformations, 2 lymphatico-venous malformations, and 1 Klippel- Trenaunay syndrome. The median injected volume was 1.00 mL/site of injection. Effects of sclerotherapy on pain, functional and cosmetic disturbance were statistically evaluated with a final result score. Local and systemic complications were recorded. Results The mean Visual Analogue Scores were 5.20±2.81 before and 1.52±1.25 after treatment (p<0.001). Functional and aesthetic improvement was achieved in 31/35 patients (89%) and in 33/41 (80%), respectively. Minor local side effects included necrosis with or without issue of ethylcellulose, palpable residue, and hematoma. No systemic side-effects occurred. Conclusion Per mL used, radio-opaque gelified ethanol is at least as effective as absolute ethanol. No systemic complica
Eur Radiol DOI 10.1007/s00330-011-2213-4 Received: 13 April 2011 / Revised: 30 May 2011 / Accepted: 20 June 2011