Interchangeability of macular thickness measurements between different volumetric protocols of Spectralis optical coherence tomography in normal eyes
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Yaroslava Wenner & Stephan Wismann & Melanie Jنger & Jِrn Pons-Kühnemann & Birgit Lorenz
- چاپ و سال / کشور: 2011
Description
Backgrounds To evaluate in healthy eyes the interchangeability of retinal thickness measurements resulting from different protocols of Spectralis optical coherence tomography (OCT, Heidelberg Engineering, Germany). Methods Three different central volumetric protocols were performed in one session by one single operator in a randomly selected eye of 31 healthy adults (range, 19. 30 years): (1) area 6پ~6 mm, 25 scan pattern (SP), (2) area 6پ~6 mm, 49 SP, (3) area 6پ~3 mm, 97 SP. Nine ETDRS areas were analyzed, except outer areas for 97 SP. Interclass correlation coefficients (ICC) and limits of agreement (Bland.Altman) were calculated. Results Mean minimal foveal thickness was 224.0پ} 15.8 ƒتm and central retinal thickness 280.8پ}16.5 ƒتm. ICC ranged from 0.973 to 0.993. Ninety-five percent limits of agreement between the protocols were <7 ƒتm in all ETDRS areas. The difference between two measurements never exceeded 9 ƒتm. Conclusions Spectralis OCT retinal thickness measurements in healthy subjects showed good protocol interchangeability for all tested protocols. Larger differences are to be expected in eyes with macular pathology.
Graefes Arch Clin Exp Ophthalmol (2011) 249:1137–1145 DOI 10.1007/s00417-011-1630-z Received: 12 September 2010 / Revised: 28 November 2010 / Accepted: 20 January 2011 / Published online: 20 February 2011
