Patient characteristics and treatment of neovascular age-related macular degeneration in France: the LUEUR1 observational study
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Salomon-Yves Cohen & Eric H. Souied & Michel Weber & Gérard Dupeyron & Gérard de Pouvourville & Michel Lievre & Anne Ponthieux
- چاپ و سال / کشور: 2010
Description
Background Age-related macular degeneration is the primary cause of blindness in developed countries. Current treatments of this degenerative disease mainly include laser, photodynamic therapy with verteporfin and administration of antivascular endothelial growth factors. The LUEUR (LUcentis® En Utilisation Réelle) study is composed of a cross-sectional part (LUEUR1), which examined the current management of wet AMD in France, and a follow-up part (LUEUR2), which will assess the development of patients treated for wet AMD over 4 years. Here we describe the results of LUEUR1. Methods Patients with wet AMD were enrolled during a routine medical examination in LUEUR1, a cross-sectional, observational, prospective, multicentre study. Investigators recorded patient demographics, visual acuity, characteristics of wet AMD lesions, date of AMD diagnosis, comorbidities, previous treatments, treatments prescribed at inclusion, and low vision rehabilitation. Results A total of 72 investigators recruited 1,019 patients with wet AMD, corresponding to 1,405 eyes affected by the disease. The mean age of patients was 78.7±7.3 years. Most were female (62.3%) and non-smokers (66.9%). The
Graefes Arch Clin Exp Ophthalmol (2011) 249:521–527 DOI 10.1007/s00417-010-1553-0 Received: 22 July 2010 / Revised: 5 October 2010 / Accepted: 17 October 2010 / Published online: 6 November 2010
