Timing of continuous veno-venous hemodialysis in the treatment of acute renal failure following cardiac surgery
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Qiang Ji Yunqing Mei Xisheng Wang Jing Feng Jianzhi Cai Yongxin Zhou Yifeng Sun Shiliang Xie Dayi Hu
- چاپ و سال / کشور: 2010
Description
The purpose was to study optimum timing of continuous veno-venous hemodialysis (CVVHD) for acute renal failure (ARF) after cardiac surgery. CVVHD was performed in two groups [elapsed time between urine output (UO) \0.5 ml/kg/h and dialysis of no more than 12 h in group A and[12 h in group B] with a total of 58 adult patients. Survivors in groups A and B were entered into groups A1 and Bl, respectively. Compared to group A, the acute physiology and chronic health evaluation III score, peak values of urea and creatinine before CVVHD, major complications, period of ICU and hospitalization were significantly higher in group B. In-hospital mortality in group B was significantly higher than that in group A (37.5 vs. 8.8%, p = 0.02). Kaplan-Meier curves confirmed significantly better postoperative survival in group A (v2 = 6.966, p = 0.008). Time elapse from UO\0.5 ml/kg/h until dialysis among the survivors was significantly lower than that among the dead (12.0 ± 6.2 vs. 20.8 ± 9.1 h, p = 0.0002). Additionally, duration of dialysis, length of ICU stay, duration of ventilator support and time elapse from dialysis until UO[1 ml/kg/h were significantly higher in group B1 as compared to those in group A1. All of them correlated positively with the time elapse from UO\0.5 ml/kg/h until dialysis. Early beginning of CVVHD is extremely important.
Heart Vessels (2011) 26:183–189 DOI 10.1007/s00380-010-0045-9 Received: 4 June 2009 / Accepted: 1 April 2010 / Published online: 10 November 2010
