Uncontrolled home blood pressure in the morning is associated with nephropathy in Japanese type 2 diabetes
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Emi Ushigome Michiaki Fukui Kazumi Sakabe Muhei Tanaka Shinobu Inada Atsushi Omoto Toru Tanaka Wataru Fukuda Haruhiko Atsuta Masayo
- چاپ و سال / کشور: 2010
Description
The purposes of this study were to investigate the state of blood pressure control level and to investigate the relationship between blood pressure control level and nephropathy in Japanese type 2 diabetes. We measured clinic and home blood pressure in 923 type 2 diabetic patients. According to the criteria for hypertension in the Japanese Society of Hypertension Guidelines 2009, patients were classified into four groups by clinic systolic blood pressure (130 mmHg) and morning systolic blood pressure (125 mmHg), as follows: controlled hypertension (CH), white-coat hypertension (WCH), masked hypertension (MH), and sustained hypertension (SH). Of all patients, 13.9, 12.6, 13.3, and 60.2% were identified as having CH, WCH, MH, and SH, respectively. The average number of drugs prescribed was 1.8. We assessed the association between blood pressure control level and nephropathy in diabetic patients. The degree of urinary albumin excretion and the prevalence of nephropathy in diabetic patients were higher in MH and SH groups than those in the CH group. The majority of patients had poor blood pressure control, regardless of ongoing conventional antihypertensive therapy, and diabetic patients with MH and SH were associated with nephropathy. It is suggested that more aggressive antihypertensive treatment is recommended to prevent nephropathy in diabetic patients.
Heart Vessels DOI 10.1007/s00380-010-0107-z Received: 16 September 2010 / Accepted: 12 November 2010
