Erratum to: Resveratrol and red wine, healthy heart and longevity
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Dipak K. Das • Subhendu Mukherjee • Diptarka Ray
- چاپ و سال / کشور: 2011
Description
Resveratrol, a polyphenol phytoalexin, present in red wine and grapes possesses diverse biochemical and physiological properties, including estrogenic, antiplatelet, and anti-inflammatory properties as well as a wide range of health benefits ranging from chemoprevention to cardioprotection. Recently, several studies described resveratrol as an anti-aging compound. This review focuses on the anti-aging aspects of resveratrol, the possible mechanisms of action, and emerging controversy on its life-prolonging ability. It appears that resveratrol can induce the expression of several longevity genes including Sirt1, Sirt3, Sirt4, FoxO1, Foxo3a and PBEF and prevent aging-related decline in cardiovascular function including cholesterol level and inflammatory response, but it is unable to affect actual survival or life span of mice.
Heart Fail Rev (2011) 16:425–435 DOI 10.1007/s10741-011-9234-6 Published online: 13 March 2011
