The pulsed dye laser for the treatment of basal cell carcinoma
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Christopher J. Ballard & Maria P. Rivas & Michael Patrick McLeod & Sonal Choudhary & George W. Elgart & Keyvan Nouri
- چاپ و سال / کشور: 2011
Description
microvasculature system that can be targeted by the 585-nm pulsed dye laser (PDL) utilizing the theory of selective photothermolysis. Seven volunteers with nine well-defined, biopsy-proven BCCs, were treated with the PDL (585-nm wavelength, a single 450-ىs pulse, 7-mm spot size, and 9.0 J/cm2 energy). The lesions, along with a 4-mm border of normal skin were treated. Pain assessment was carried out immediately after the laser treatment. A deep shave biopsy with histological examination occurred 4 weeks after the laser treatment. Pain was assessed on a scale of 0 (no pain) to 10 (worst pain possible). The average patient score was 2.1 (range 1–4). On histology, 5/9 (55.6%) sites demonstrated no evidence of BCC; however, 4/9 (44.4%) sites showed residual BCC. Although the PDL was able to clear over half of the BCCs in this study, there was an unacceptably high persistence rate of 44.4%. The PDL did not achieve the clearance rate that can be attained with current standard BCC treatment modalities. At this time, we do not recommend that a single treatment with the 585-nm PDL can be used as a primary therapy for BCC.
Lasers Med Sci (2011) 26:641–644 DOI 10.1007/s10103-011-0952-8 Received: 8 November 2010 / Accepted: 20 June 2011 / Published online: 12 July 2011
