Ultra-low-level laser therapy
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Luigi Baratto & Laura Calzà & Roberto Capra & Michele Gallamini & Luciana Giardino & Alessandro Giuliani & Luca Lorenzini & Silvano Traverso
- چاپ و سال / کشور: 2011
Description
A growing number of laboratory and clinical studies over the past 10 years have shown that low-level laser stimulation (633 or 670 nm) at extremely low power densities (about 0.15 mW/cm2), when administered through a particular emission mode, is capable of eliciting significant biological effects. Studies on cell cultures and animal models as well as clinical trials give support to a novel therapeutic modality, which may be referred to as ultra low level laser therapy (ULLLT). In cultured neural cells, pulsed irradiation (670 nm, 0.45 mJ/cm2) has shown to stimulate NGF-induced neurite elongation and to protect cells against oxidative stress. In rats, anti-edema and antihyperalgesia effects following ULLL irradiation were found. Clinical studies have reported beneficial effects (also revealed through sonography) in the treatment of musculoskeletal disorders. The present paper reviews the existing experimental evidence available on ULLLT. Furthermore, the puzzling issue of the biophysical mechanisms that lie at the basis of the method is explored and some hypotheses are proposed. Besides presenting the state-ofthe- art about this novel photobiostimulation therapy, the present paper aims to open up an interdisciplinary discussion and stimulate new research on this subject
Lasers Med Sci (2011) 26:103–112 DOI 10.1007/s10103-010-0837-2 Received: 25 May 2010 / Accepted: 24 August 2010 / Published online: 18 September 2010
