Effects of 940 nm light-emitting diode (led) on sciatic nerve regeneration in rats
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Karla Guivernau Gaudens Serafim & Solange de Paula Ramos & Franciele Mendes de Lima & Marcelo Carandina & Osny Ferrari & Ivan Frederico Lupiano Dias
- چاپ و سال / کشور: 2011
Description
The objective of the present study was to evaluate the effect of 940 nm wavelength light emitting diode (LED) phototherapy on nerve regeneration in rats. Forty male Wistar rats weighing approximately 300 g each were divided into four groups: control (C); control submitted to LED phototherapy (CLed); Sciatic Nerve Lesion without LED phototherapy (L); Sciatic Nerve Lesion with LED phototherapy (LLed). The lesion was caused by crushing the right sciatic nerve. A dose of 4 J/cm2 was used for ten consecutive days beginning on the first postoperative day. Groups C and L were submitted to the same procedure as the LLed group, but the equipment was turned off. The LED phototherapy with 940 nm wavelength reduced the areas of edema, the number of mononuclear cells present in the inflammatory infiltration, and increased functional recovery scores at 7, 14 and 21 days. The results suggest that the use of phototherapy at 940 nm after nerve damage improves morphofunctional recovery and nerve regeneration.
Lasers Med Sci DOI 10.1007/s10103-011-0923-0 Received: 20 September 2010 / Accepted: 6 April 2011
