Accuracy of pre-surgical fMRI confirmed by subsequent crossed aphasia
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Paolo Vitali • Nina Dronkers • Alexander Pincherle • Anna Rita Giovagnoli • Carlo Marras • Ludovico D’Incerti • Francesco Ghielmetti • Roberto Sprea
- چاپ و سال / کشور: 2010
Description
Atypical patterns of language activation in functional MRI (fMRI) are not unusual, particularly in patients with severe epilepsy. Still, the functional significance of these activations is under debate. We describe a case of a right-handed patient affected by drug-refractory right temporal lobe epilepsy in whom pre-surgical fMRI showed bilateral language activations, greater in the right hemisphere (RH). After surgery, a right subdural hematoma caused epileptic status and severe aphasia. This post-surgical complication of a crossed aphasia confirmed the prior fMRI findings of RH language thus stressing the value of pre-surgical fMRI evaluations, even when surgery is planned in the RH of a right-handed patient.
Neurol Sci (2011) 32:175–180 DOI 10.1007/s10072-010-0426-y Received: 30 November 2009 / Accepted: 8 September 2010 / Published online: 19 November 2010
