Steroid-responsive Hashimoto encephalopathy mimicking Creutzfeldt–Jakob disease
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Domenico Santoro • Irene Colombo • Isabella Ghione • Lorenzo Peverelli • Nereo Bresolin • Monica Sciacco • Alessandro Prelle
- چاپ و سال / کشور: 2011
Description
Hashimoto’s encephalopathy (HE) is a rare neurological disorder with a heterogeneous group of neurological symptoms associated with high titres of antithyroid antibodies. Clinical manifestations may include encephalopathic features such as seizures, behavioural and psychiatric manifestations, movement disorders and coma. The objective of this presentation is to describe a patient with this rare and controversial clinical syndrome mimicking Creutzfeldt–Jakob disease, associated with a Hashimoto euthyroid thyroiditis and with a significant response to high dose intravenous prednisone. The responsiveness of this syndrome to steroids suggests that this disorder involves immune pathogenic mechanisms, as previous reviews reported.
Neurol Sci (2011) 32:719–722 DOI 10.1007/s10072-011-0610-8 Received: 27 May 2010 / Accepted: 27 April 2011 / Published online: 10 May 2011
