Two cases of dementias with motor neuron disease evaluated by Pittsburgh compound B-positron emission tomography
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Yoshihiro Yamakawa • Hiroyuki Shimada • Suzuka Ataka • Akiko Tamura • Hideki Masaki • Hiroshi Naka • Tsuyoshi Tsutada • Aki Nakanishi • Susumu Shiom
- چاپ و سال / کشور: 2011
Description
We described the cases of two patients with dementia associated with motor neuron disease, the former with frontotemporal dementia (FTD) and the latter with Alzheimer’s disease (AD), studied by the Pittsburgh compound B-positron emission tomography (PIB-PET). In the FTD patient, the PIB-PET revealed no amyloid accumulation in the cortex, whilst in the AD patient showed amyloid accumulation mainly in the frontal, parietal and lateral temporal lobes, besides the posterior cingulate gyrus and the precuneus. Thus, PIB-PET might facilitate the discrimination of different proteinopathies that cause neurodegenerative diseases, as dementia associated with ALS.
Neurol Sci DOI 10.1007/s10072-011-0479-6 Received: 1 August 2010 / Accepted: 11 January 2011
