Continuous involuntary hand movements and schizencephaly: epilepsia partialis continua or dystonia?
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Lucio Marinelli • Laura Bonzano • Laura Saitta • Carlo Trompetto • Giovanni Abbruzzese
- چاپ و سال / کشور: 2011
Description
Schizencephaly is regarded as a malformation of cortical development (due to abnormal neuronal organization) and may be associated with continuous involuntary hand movements. The mechanisms underlying these movements are not clear and both dystonia and epilepsia partialis continua have been considered in previously reported cases. We describe a young patient affected by schizencephaly and continuous involuntary movements of the contralateral hand. Functional MRI showed bilateral cerebral activation, while the subject performed tapping movements with the affected hand and no significant difference in the activation pattern after diazepam infusion. Standard and back-averaged EEG showed no alterations. The results obtained from these investigations and the clinical features of the involuntary movements are not in favor of an epileptic genesis, while support the diagnosis of secondary dystonia.
Neurol Sci DOI 10.1007/s10072-011-0674-5 Received: 11 January 2011 / Accepted: 20 June 2011
