Neurosyphilis presenting with psychotic symptoms and status epilepticus
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Yuanrong Yao • Enqiang Huang • Bingdi Xie • Yan Cheng
- چاپ و سال / کشور: 2011
Description
The widespread use of antibiotics in recent years has considerably modified the clinical features of neurosyphilis. Presently, atypical or masked forms of this disease often occur and obscure diagnosis, despite a thorough history and clinical work-up. Here, we report a patient with neurosyphilis presenting with psychotic symptoms who then developed status epilepticus and left limb weakness. Diffusion-weighted magnetic resonance imaging showed hyperintensity involving the right parietal, occipital and temporal lobes and the thalamus. Subsequent serological and cerebrospinal fluid tests confirmed the diagnosis of neurosyphilis. The coexistence of meningovascular syphilis, syphilitic meningitis, and general paresis resulted in the complex manifestation of this patients’ condition, as described here in terms of the unusual presentation, evolution, and final diagnosis.
Neurol Sci DOI 10.1007/s10072-011-0563-y Received: 3 May 2010 / Accepted: 19 March 2011