Mammillotegmental tract in the human brain: diffusion tensor tractography study
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Hyeok Gyu Kwon & Ji Heon Hong & Sung Ho Jang
- چاپ و سال / کشور: 2011
Description
Introduction Several animal studies have been conducted for the identification of the mammillotegmental tract (MTT); however, no study has been reported in the human brain. Methods In the current study, using diffusion tensor tractography (DTT), we attempted to identify the MTT in the human brain. We recruited 31 healthy volunteers for this study. Diffusion tensor images were acquired using 1.5 T, and the MTT was obtained using a probabilistic tractography method based on a multi-fiber model. Values of fractional anisotropy, mean diffusivity, and tract volume of the MTT were measured. Results MTTs of all subjects, which originated from the mammillary body, ascended posteriorly to the bicommissural level along the third ventricle and then turned caudally and terminated at the tegmentum of the midbrain. No significant differences were observed in terms of fractional anisotropy, mean diffusivity, and tract volume according to hemisphere and sex (P<0.05). Using DTT, we identified the MTT in the human brain. Conclusion We believe that the methodology and results of this study would be helpful in research on the MTT in the human brain.
Neuroradiology (2011) 53:623–626 DOI 10.1007/s00234-011-0858-y Received: 15 November 2010 / Accepted: 2 March 2011 / Published online: 3 May 2011
