Does Surgically Induced Weight Loss Improve Daytime Sleepiness?
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Jon-Erik Cleophas Holty & Neeta Parimi & Michael Ballesteros & Terri Blackwell & Paul T. Cirangle & Gregg H. Jossart & Nicole D. Kimbrough & Jennifer
- چاپ و سال / کشور: 2010
Description
Morbid obesity is associated with excessive daytime sleepiness and reduced health-related quality of life. We prospectively evaluated the pre- and postoperative responses of bariatric surgery recipients with the Epworth Sleepiness Scale (ESS) and the Short Form-12. Participants (n=223; 79% women) with a mean body mass index (BMI) and ESS of 44.8±7.9 kg/m2 and 7.9±4.5, respectively, received a vertical gastrectomy (76%) or Roux-en-Y gastric bypass (12%). Preoperatively, 30% of patients complained of excessive daytime sleepiness (ESS>10). Patients with preoperative excessive daytime sleepiness were more obese (p=0.002), had higher fasting glucose levels (p=0.02), more likely to have a diagnosis of sleep-disordered breathing (p<0.001), report snoring (p<0.001), and had lower health-related quality of life measures particularly physical function (p<0.001), depression (p=0.006), and sexual satisfaction (p=0.04) than non-sleepy patients. At 12-months postoperatively, most patients experienced a significant reduction in BMI (28.6±5.5 kg/m2, p<0.001) and excessive daytime sleepiness (mean ESS 5.3±3.3, p< 0.001). Patients with a clinically relevant improvement in the ESS at 12-months post-operatively had greater improvements in physical function (p=0.009) and snoring (p= 0.010) and were more likely still using positive airway pressure therapy (p=0.032) than patients without a clinically relevant improvement. Statistically and clinically significant improvements in all health-related quality of life measures were noted at 24 months. Bariatric surgery is associated with dramatic weight loss and improvements in physical functioning and daytime sleepiness.
OBES SURG DOI 10.1007/s11695-010-0213-0
