Nicorandil-induced tongue ulceration with or without fungal infection
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Haruhiko Terai • Hirohisa Yamanishi • Masashi Shimahara
- چاپ و سال / کشور: 2011
Description
Oral ulceration is one of the common adverse effects of nicorandil in European countries. In Japan, however, only 9 cases of nicorandil-induced oral ulceration have been reported. Here, we report 3 cases of nicorandilinduced oral ulceration, one of which exhibited a unique clinical course associated with Candida infection. In this case, the initial discontinuation of nicorandil failed to ameliorate the lesion. However, the second discontinuation of the drug after the control of the Candida infection overlying the surface of the ulcer produced a favorable effect. This patient was diagnosed with nicorandil-induced tongue ulceration with Candida infection.
Odontology DOI 10.1007/s10266-011-0015-4