Age-related decline in bone density among ethnically diverse older men
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Y. Sheu & J. A. Cauley & V. W. Wheeler & A. L. Patrick & C. H. Bunker & K. E. Ensrud & E. S. Orwoll & J. M. Zmuda & for the Osteoporotic Fracture i
- چاپ و سال / کشور: 2010
Description
Summary We compared rates of BMD decline in older men of diverse ethnic backgroud. The rate of bone loss was statistically equivalent between men of African and Caucasian descent. Introduction Race differences in peak bone mineral density (BMD) are well established, but the magnitude of bone loss among non-white men has not been well characterized. Our objective was to compare and contrast the rates of decline in BMD with aging among older men of different race/ ethnic groups. Methods The rate of decline in hip BMD was measured by dual-energy X-ray absorptiometry (Hologic QDR-4500 W) with an average follow-up of 4.6 years in 3,869 Caucasian, 138 African American, 145 Asian, and 334 Afro-Caribbean men aged.65 years (Mean ages: 73پ}5, 70پ}4, 72پ}5, 71پ} 5 years, respectively). Results The annual rate of decline in BMD at the femoral neck was .0.32%, .0.42%, .0.09%, and .0.44%/year for Caucasian, African American, Asian, and Afro-Caribbean men, respectively (p<0.05 for Caucasian versus Asian). Although men of African ancestry have higher peak BMD than Caucasians, rates of decline in BMD with aging appear to be statistically equivalent in our study. In contrast, Asian men experienced a slower rate of decline in BMD compared with Caucasians and African Americans. Conclusion More studies are needed to better define the natural history of and factors associated with bone loss among non-white men.
Osteoporos Int (2011) 22:599–605 DOI 10.1007/s00198-010-1330-2 Received: 29 January 2010 / Accepted: 3 June 2010 / Published online: 22 June 2010
