A Case of Cor Triatriatum With an Abnormal P Wave: The Pacemaker Action From the Specialized Tissue in the Abnormal Septum
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Yoshimichi Kudo • Mariko Kaneko • Makoto Nakazawa • Sachiko Tomita
- چاپ و سال / کشور: 2011
Description
A boy presented with an abnormal P wave shown on an electrocardiogram (ECG) checkup at school. An echocardiogram and contrast-enhanced computed tomography (CT) showed cor triatriatum with a slit-like opening between the accessory chamber and the left atrium located along the interatrial septum. The boy underwent open heart surgery for excision of the anomalous membrane, and a postoperative ECG showed normal P waves. The excised tissue was examined immnunohistopathologically using antihyperpolarization-activated cyclic nucleotide- gated potassium channel 4 (HCN4) antibody and other staining. The authors confirmed the existence of cells positive to HCN4, indicating that they were sinoatrial node cells or at least cells with electrical automaticity.
Pediatr Cardiol DOI 10.1007/s00246-011-0078-6 Received: 14 April 2011 / Accepted: 20 July 2011
