Early identification of steroid dependency in Japanese children with steroid-sensitive nephrotic syndrome undergoing short-term initial steroid therapy
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Shuichiro Fujinaga & Daishi Hirano & Naoto Nishizaki
- چاپ و سال / کشور: 2011
Description
Sirs, We read with great interest the article titled “Early age at debut is a predictor of steroid-dependent and frequent relapsing nephrotic syndrome” by Andersen et al. recently published in Pediatric Nephrology [1]. In a retrospective analysis of 54 children (approximately 80% Caucasian) with steroid-sensitive nephrotic syndrome (SSNS), the authors concluded that young age at presentation and male gender were associated with a high risk of steroid dependency despite prolongation of the steroid course at the debut of SSNS. In addition, they found a reduction in relapse frequency in the long-term initial steroid therapy group (12 weeks) compared with the short-term group (8 weeks).
Pediatr Nephrol (2011) 26:485–486 DOI 10.1007/s00467-010-1642-7 Received: 26 July 2010 / Revised: 27 July 2010 / Accepted: 2 August 2010 / Published online: 21 August 2010
