Suggested revision of the National High Blood Pressure  Education Program blood pressure standardization  for use in severely growth retarded children

Suggested revision of the National High Blood Pressure Education Program blood pressure standardization for use in severely growth retarded children

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : Karlijn J. van Stralen & Kitty J. Jager & Enrico Verrina & Franz S. Schaefer & Francesco Emma
  • چاپ و سال / کشور: 2011

Description

In 2007, the updated 4th report of the National High Blood Pressure Education Program was published [1] (http://www. nhlbi.nih.gov/health/prof/heart/hbp/hbp_ped.pdf). This report represents an international standard for the evaluation, diagnosis, and treatment of high blood pressure (BP) in the pediatric population and is based on data collected from 63,227 non-obese US children. BP measurements can be expressed as standard deviation scores (SDS) by subtracting the child’s expected blood pressure, based on age and height percentiles, from the measured blood pressure and by dividing the resulting difference by one standard deviation. To correct BP for the height z score, the authors have used fourth-degree polynomial regression models [2], also reported in appendix B of the report [1]. These models, one for each gender and for both systolic and diastolic blood pressures, are very useful to generate standardized measurements. They are often used both in clinical practice and in the context of clinical trials and constitute the basis on which blood pressure tables have been generated [1, 2]. However, these models were developed on data from healthy children with expected normal heights, while children with grossly abnormal height z scores (< -6 and >6) were excluded.
Pediatr Nephrol (2011) 26:819–820 DOI 10.1007/s00467-010-1738-0 Received: 17 November 2010 / Accepted: 25 November 2010 / Published online: 31 December 2010
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