A patient with polyuria and hydronephrosis: answer
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Graciana Jaureguiberry & William van’t Hoff & Imran Mushtaq & Divyesh Desai & Nicholas P. Mann & Robert Kleta & Daniel G. Bichet & Detlef Bockenhaue
- چاپ و سال / کشور: 2011
Description
The case demonstrates the importance of assessing NDI and hydronephrosis separately. Hydronephrosis is a recognised complication of primary NDI and thought to be secondary to the high urine flow [2–5]. The danger, however, is to automatically assume this causality, as these conditions can also occur independently in the same patient. Whilst both are rare diseases, with an estimated incidence of 1 in 5000 (PUV) and 1 in 1,000,000 (X-linked NDI) boys, they are not mutually exclusive, and co-occurrence was indeed reported previously, albeit without genetic confirmation of the NDI as the underlying gene was not known at the time [6–8]. Here, the key finding suggesting a separate cause for the hydronephrosis was the trabeculated appearance of the bladder on ultrasound (Fig. 1c).
Pediatr Nephrol DOI 10.1007/s00467-011-1782-4 Received: 22 October 2010 / Revised: 17 December 2010 / Accepted: 5 January 2011
