Hemodiafiltration: the addition of convective flow to hemodialysis
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Michel Fischbach & Helen Fothergill & Arianne Zaloszyc & Laure Seuge
- چاپ و سال / کشور: 2011
Description
Hemodiafiltration (HDF) combines both hemofiltration (HF) and hemodialysis in the same procedure. It was initially performed in adults in 1977, and later used in children in the early 1980s. The use of HDF allows a determined convective dialysis dose to be combined with the conventional urea dialysis dose. The dialysis session is better tolerated as a result of the effects of hemofiltration. On-line HDF, i.e., substitution fluid prepared from ultrafiltration of the ultrapure dialysate, can be performed safely due to recent advances in modern technology. However, despite interest and feasibility in children, the majority of pediatric dialysis units across the world still perform hemodialysis using highly permeable membranes, allowing back filtration in the filter and therefore a degree of convective flow, i.e., internal hemodiafiltration. In some countries, government restrictions prohibit the use of online hemodiafiltration, (such as the FDA recommendations in North America), and therefore it should not be used in these circumstances.
Pediatr Nephrol DOI 10.1007/s00467-011-1779-z Received: 18 October 2010 / Revised: 18 December 2010 / Accepted: 10 January 2011