An unusual DMSA scan—Question

An unusual DMSA scan—Question

  • نوع فایل : کتاب
  • زبان : انگلیسی
  • مؤلف : Alison Timmis & Caroline Jones & Fauzia Paize
  • چاپ و سال / کشور: 2011

Description

A 4-year-old boy presented at the age of 2 with a urinary tract infection (UTI) associated with a febrile illness. Urine culture grew Escherichia coli at >105 organisms/ml. He received a treatment course of antibiotics and was then commenced on antibiotic prophylaxis. An initial renal ultrasound performed 1 week after treatment of the urinary tract infection had been initiated was normal, demonstrating kidneys measuring 5.1 cm on the right and 6 cm on the left. A DMSA (dimercaptosuccinic acid) scan that was carried out 7 weeks after treatment of the UTI demonstrated only a small amount of uptake by both kidneys (Fig. 1). Renal function was normal based on a serum creatinine (Cr) measurement of 49 ىmol/l. The DMSA scan was repeated 8 months later due to the unusual appearance of the kidneys on the first scan in a child with normal renal function. Once again the scan demonstrated no fixation of 99mTc-DMSA in the kidneys, and again the child’s renal function was normal, with a Cr measurement of 34 ىmol/l. Following these unusual findings a MAG3 renogram was conducted, which confirmed that both kidneys were functioning normally, based on normal perfusion, uptake and excretion of the radioisotope (Figs. 2, 3). Relative uptake at 3 min was 49% on the left and 51% on the right. A micturating cystourethrogram (MCUG) showed no vesicoureteric reflux.
Pediatr Nephrol DOI 10.1007/s00467-011-1912-z Received: 10 November 2010 / Revised: 28 April 2011 / Accepted: 29 April 2011
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