Improved cardiovascular flow quantification with time-resolved volumetric phase-contrast MRI
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Albert Hsiao & Marcus T. Alley & Payam Massaband & Robert J. Herfkens & Frandics P. Chan & Shreyas S. Vasanawala
- چاپ و سال / کشور: 2010
Description
Background Cardiovascular flow is commonly assessed with two-dimensional, phase-contrast MRI (2-D PC-MRI). However, scan prescription and acquisition over multiple planes is lengthy, often requires direct physician oversight and has inconsistent results. Time-resolved volumetric PCMRI (4-D flow) may address these limitations. Objective We assess the degree of agreement and internal consistency between 2-D and 4-D flow quantification in our clinical population. Materials and methods Software enabling flow calculation from 4-D flow was developed in Java. With IRB approval and HIPAA compliance, 18 consecutive patients without shunts were identified who underwent both (1) conventional 2-D PC-MRI of the aorta and main pulmonary artery and (2) 4-D flow imaging. Aortic and pulmonary flow rates were assessed with both techniques. Results Both methods showed general agreement in flow rates (ñ: 0.87–0.90). Systemic and pulmonary arterial flow rates were well-correlated (ñ: 4-D 0.98–0.99, 2-D 0.93), but more closely matched with 4-D (P < 0.05, Brown- Forsythe). Pulmonary flow rates were lower than systemic rates for 2-D (P < 0.05, two-sample t-test). In a sub-analysis of patients without pulmonary or aortic regurgitation, 2-D showed improved correlation of flow rates while 4-D phase-contrast remained tightly correlated (ñ: 4-D 0.99– 1.00, 2-D 0.99). Conclusion 4-D PC-MRI demonstrates greater consistency than conventional 2-D PC-MRI for flow quantification.
Pediatr Radiol (2011) 41:711–720 DOI 10.1007/s00247-010-1932-z Received: 1 September 2010 / Revised: 30 October 2010 / Accepted: 12 November 2010 / Published online: 11 January 2011
