Accuracy of CT-guided percutaneous core needle biopsy for assessment of pediatric musculoskeletal lesions
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Anastasia L. Hryhorczuk & Peter J. Strouse & J. Sybil Biermann
- چاپ و سال / کشور: 2010
Description
Background CT-guided percutaneous core needle biopsy has been shown in adults to be an effective diagnostic tool for a large number of musculoskeletal malignancies. Objective To characterize our experience with CT-guided percutaneous core needle biopsy of pediatric bone lesions and determine its utility in diagnosing pediatric osseous lesions, in a population where such lesions are commonly benign. Materials and methods From 2000 to 2009, 61 children underwent 63 CT-guided percutaneous biopsies. Radiological, pathological and clinical records were reviewed. Results Fourteen biopsies (22%) were performed onmalignant lesions, while 49 biopsies (78%) were performed on benign lesions. Forty-nine of the 63 biopsies (78%) were adequate; these children underwent no further tissue sampling. Fourteen of the 63 biopsies (22%) were inadequate or non-conclusive. Of these patients, 12 underwent open biopsy. Retrospective analysis of percutaneous biopsies in these patients demonstrates that 9/12 provided clinically relevant information, and 4/12 patients received final diagnoses that confirmed initial core biopsy findings. No malignancies were diagnosed as benign on percutaneous biopsy. Overall, percutaneous core needle biopsy provided accurate diagnostic information in 84% (53/63) of biopsies. Conclusion Our results demonstrate that CT-guided percutaneous biopsy is safe and beneficial in children. This study supports the use of CT-guided percutaneous core needle biopsy for primary diagnosis of pediatric bone lesions.
Pediatr Radiol (2011) 41:848–857 DOI 10.1007/s00247-010-1970-6 Received: 2 September 2010 / Revised: 27 November 2010 / Accepted: 17 December 2010 / Published online: 18 January 2011
