Evaluation of image quality and radiation dose at prospective ECG-triggered axial 256-slice multi-detector CT in infants with congenital heart disease
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Mei-ping Huang & Chang-hong Liang & Zhen-jun Zhao & Hui Liu & Jing-lei Li & Jin-e Zhang & Yan-hai Cui & Lin Yang & Qi-shun Liu & Thomas B. Ivanc & Ma
- چاپ و سال / کشور: 2010
Description
Background There are a limited number of reports on the technical and clinical feasibility of prospective electrocardiogram (ECG)-gated multi-detector computed tomography (MDCT) in infants with congenital heart disease (CHD). Objective To evaluate image quality and radiation dose at weight-based low-dose prospectively gated 256-slice MDCT angiography in infants with CHD. Materials and methods From November 2009 to February 2010, 64 consecutive infants with CHD referred for preoperative or post-operative CTwere included. All were scanned on a 256-slice MDCT system utilizing a low-dose protocol (80 kVp and 60.120 mAs depending on weight: 60 mAs for .3 kg, 80 mAs for 3.1.6 kg, 100mAs for 6.1.10 kg, 120 mAs for 10.1.15 kg). Results No serious adverse events were recorded. A total of 174 cardiac deformities, confirmed by surgery or heart catheterization, were studied. The sensitivity of MDCT for cardiac deformities was 97.1%; specificity, 99.4%; accuracy, 95.9%. The mean heart rate during scan was 136.7} 14.9/min (range, 91.160) with a corresponding heart rate variability of 2.8}2.2/min (range, 0.8). Mean scan length was 115.3}11.7 mm (range, 93.6.143.3). Mean volume CT dose index, mean dose-length product and effective dose were 2.1}0.4 mGy (range, 1.5.2.8), 24.7}5.9 mGyEcm (range, 14.7.35.8) and 1.6}0.3 mSv (range, 1.1.2.5), respectively. Diagnostic-quality images were achieved in all cases. Satisfactory diagnostic quality for visualization of all/proximal/distal coronary artery segments was achieved in 88.4/98.8/80.0% of the scans. Conclusion Low-dose prospectively gated axial 256-slice CT angiography is a valuable tool in the routine clinical evaluation of infants with CHD, providing a comprehensive three-dimensional evaluation of the cardiac anatomy, including the coronary arteries.
Pediatr Radiol (2011) 41:858–866 DOI 10.1007/s00247-011-2079-2 Received: 13 August 2010 / Revised: 11 December 2010 / Accepted: 11 December 2010 / Published online: 2 May 2011
