Octreotide in the treatment of neonatal postoperative chylothorax: report of three cases and literature review
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Joaکo Moreira-Pinto • Paula Rocha • Ange´lica Oso´rio • Berta Bonet • Fa´tima Carvalho • Carlos Duarte • Lu´sa Oliveira
- چاپ و سال / کشور: 2011
Description
Chylothorax is a well-recognized complication after neonatal cardiothoracic surgery. Management strategies include cessation of enteral feedings, repeated aspiration, chest drainage, and total parenteral nutrition. Somatostatin and its analogue, octreotide, have been used with promising results. The authors present three cases of neonatal postoperative chylothorax in which octreotide was used. After literature review, we can say that octreotide is relatively safe, and may reduce clinical course and complications associated with neonatal postoperative chylothorax. One should be aware of possible association between octreotide and necrotizing enterocolitis. Prospective controlled trials supporting octreotide use are lacking.
Pediatr Surg Int (2011) 27:805–809 DOI 10.1007/s00383-010-2730-2 Accepted: 26 August 2010 / Published online: 7 September 2010