The Protection Potential of an Alum-Adjuvanted F1 Protein in Dry Powder against Plague in Mice
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : Wang Wang, Yiran Liu, Xiangna Zhao, Zongmin Du, Yafang Tan, Yujing Bi, Yanping Han, Ruifu Yang* and Xiaoyi Wang*
- چاپ و سال / کشور: 2010
Description
Aluminum hydroxide is the only adjuvant for use in human vaccines. The commercial alum-adjuvanted vaccines are formulated as liquid without exception. We prepared an alum-adjuvanted dry powder vaccine and demonstrated that it provided good protection for plague. The preparation strategy is simple and effective, and can be carried out in a large scale. The dry powder vaccine can be quickly reconstituted using sterile water for injection. The dry powder vaccines have potential advantages over liquid vaccines, including good stability and extended shelf life.
J Vaccines Vaccin ISSN:2157-7560 JVV an open access journa lVolume 1• Issue 2•1000105Citation: Wang W, Liu Y, Zhao X, Du Z, Tan Y, et al. (2010) The Protection Potential of an Alum-Adjuvanted F1 Protein in Dry Powder against Plague in Mice. J Vaccines Vaccin 1: 105. doi:10.4172/2157-7560.1000105