Biopharmaceuticals, expression host systems, production, purification and analysis of rDNA, recombinant therapeutic proteins
- نوع فایل : کتاب
- زبان : انگلیسی
- مؤلف : G. M. Bhopale* and R. K. Nanda
- چاپ و سال / کشور: 2005
Description
Recombinant DNA (rDNA) technology has made a revolutionary impact in the area of human healthcare by enabling mass production of safe, pure and effective rDNA expression products. Currently, several categories of rDNA products, viz. hormones of therapeutic interest, haemopoietic growth factors, blood coagulation products, thrombolytic agents, anticoagulants, interferons, interleukins and therapeutic enzymes are being produced using rDNA technology for human use. The present article provides information on different aspects, viz. expression systems, production, purification, analysis and therapeutic applications of rDNA products. Further, future of rDNA products and Indian scenario are also highlighted. This article should be beneficial to biotechnology scientists and manufacturers of biopharmaceuticals.
CURRENT SCIENCE, VOL. 89, NO. 4, 25 AUGUST 2005