Long-Term Follow-Up of Patients Immunized with AN1792: ...
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Getting a Grip on Complexes
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Long-Term Follow-Up of Patients ...
Background: Immunization of patients with Alzheimer’s disease (AD) with synthetic amyloid-.. peptide (A..42) (AN1792) was previously studied in a ran ...
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Depression and Quality of Life ...
Diabetes patients are known to have a worse quality of life than individuals without diabetes. They also have an increased risk for depressive sympto ...
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Natural Non-Trasgenic Animal Mo ...
The most common animal models currently used for Alzheimer disease (AD) research are transgenic mice that express a mutant form of human A.. precurso ...
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Inflammatory Systemic Biomarker ...
Clinicians have used additional tools to aid clinical assessment and to enhance their ability to identify the “vulnerable” patient at risk for cardio ...
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Towards Retinoid Therapy for Al ...
Alzheimer’s disease(AD) is associated with a variety of pathophysiological features, including amyloid plaques, inflammation, immunological changes, ...
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Anti-Apoptotic Genes in the Sur ...
Macrophages are cells of the immune system that protect organisms against invading pathogens by fulfilling critical roles in innate and adaptive immu ...
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CENPA a Genomic Marker for Cent ...
Inheritance of genetic material requires that chromosomes segregate faithfully during cell division. Failure in this process can drive to aneuploidy ...
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Signal Processing for Metagenom ...
Traditionally, studies in microbial genomics have focused on single-genomes from cultured species, thereby limiting their focus to the small percenta ...
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Pharmacological Characteristics ...
K201 is a 1,4-benzothiazepine derivative that is a promising new drug with a strong cardioprotective effect. We initially discovered K201 as an effec ...
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The Biology of TRAIL and the Ro ...
TNF-related apoptosis inducing ligand (TRAIL) is a key mediator of the innate immune response to infection. While TRAIL-mediated apoptosis plays an e ...
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Potential Uses of MicroRNA in L ...
Lung cancer is the leading cause of death from cancer in the world. Although the molecular network of lung carcinogenesis has been partly known at th ...
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Potential of DNMT and its Epige ...
Lung cancer, the leading cause of mortality in both men and women in the United States, is largely diagnosed at its advanced stages that there are no ...
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Hidden Markov Models and their ...
Hidden Markov models (HMMs) have been extensively used in biological sequence analysis. In this paper, we give a tutorial review of HMMs and their ap ...
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Two Diseases with One Hit: Inhi ...
Obesity is a well-recognized cancer risk factor. The increase in risk for colorectal, endometrial, breast and esophageal cancers associated with obes ...
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Recent Advances in Intervention ...
Markovian regulatory networks constitute a class of discrete state-space models used to study gene regulatory dynamics and discover methods that bene ...
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Performance of Feature Selectio ...
High-throughput biological technologies offer the promise of finding feature sets to serve as biomarkers for medical applications; however, the sheer ...
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Activated Protein C and Acute K ...
Protein C is a plasma serine protease that when activated plays a central role in modulating the function of the vascular endothelium and its interfa ...
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Functional Characterization of ...
Chitin and its deacetylated derivative chitosan are natural polymers composed of randomly distributed ..-(1-4)- linked D-glucosamine (deacetylated un ...
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Classification and Error Estima ...
Discrete classification is common in Genomic Signal Processing applications, in particular in classification of discretized gene expression data, and ...
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Tumor Systems Need to be Render ...
Background: A tumor system not only consists of diverse cell types but also comprises all components of action insofar that these components are orie ...
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Baseline MRI Predictors of Conv ...
The Alzheimer’s Disease Neuroimaging Initiative (ADNI) is a multi-center study assessing neuroimaging in diagnosis and longitudinal monitoring. Amnes ...
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p53 isoform D113p53 is a p53 ta ...
p53 is a well-known tumor suppressor and is also involved in processes of organismal aging and developmental control. A recent exciting development i ...
1.84 MB
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Clustering Algorithms: On Learn ...
The development of microarray technology has enabled scientists to measure the expression of thousands of genes simultaneously, resulting in a surge ...
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Review of Peak Detection Algori ...
In this review, we will discuss peak detection in Liquid-Chromatography-Mass Spectrometry (LC/MS) from a signal processing perspective. A brief intro ...
1.68 MB
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Getting a Grip on Complexes
We are witnessing tremendous advances in our understanding of the organization of life. Complete genomes are being deciphered with ever increasing sp ...
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