Haplotypes in SLC24A5 Gene as Ancestry Informative Mark ...
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Genetics in Osteoarthritis
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Haplotypes in SLC24A5 Gene as A ...
Ancestry informative markers (AIMs) are human polymorphisms that exhibit substantially allele frequency differences among populations. These markers ...
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Cancer Metastasis as Disrupted ...
Cancer metastasis is a complex processes, associated with the invasion to tissues with extensive degradation of the surrounding normal components, pe ...
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Simulation of Genomes: A Review
There is an increasing role of population genetics in human genetic research linking empirical observations with hypotheses about sequence variation ...
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Genetics in Osteoarthritis
Osteoarthritis is a degenerative articular disease with complex pathogeny because diverse factors interact causing a process of deterioration of the ...
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Internet Resources for Gene Exp ...
The number of online databases and web-tools for gene expression analysis in Arabidopsis thaliana has increased tremendously during the last years. T ...
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Genomic Instability and Carcino ...
Cancers arise as a result of stepwise accumulation of mutations which may occur at the nucleotide level and/or the gross chromosomal level. Many canc ...
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Gene Expression Profiling as a ...
The identification of quantitative trait loci, QTL, in arthritis animal models is a straight forward process. However, to identify the underlying gen ...
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Array-Based Approaches for the ...
Carcinogenesis involves the inactivation or inhibition of genes that function as tumor suppressors. Deletions, mutations, or epigenetic silencing of ...
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Molecular Genetics of Alcohol D ...
Alcohol dependence is a worldwide public health problem, and involves both environmental and genetic vulnerability factors. The heritability of alcoh ...
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The Epigenetic Origin of Aneupl ...
Theodore Boveri, eminent German pathologist, observed aneuploidy in cancer cells more than a century ago and suggested that cancer cells derived from ...
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A Survey of Chloroplast Protein ...
Protein phosphorylation is a major mode of regulation of metabolism, gene expression and cell architecture. In chloroplasts, reversible phosphorylati ...
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Pan-Vertebrate Toll-Like Recept ...
Human toll-like receptors (TLRs) recognize pathogen-associated molecular patterns (PAMPs) to raise innate immune responses. The human TLR family was ...
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The Genomics of Colorectal Canc ...
The concept of the adenoma-carcinoma sequence, as first espoused by Morson et al. whereby the development of colorectal cancer is dependent on a step ...
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Analysis of the Fragile X Trinu ...
Fragile X Syndrome (FXS) is associated with an unstable CGG repeat sequence in the 5’ untranslated region in the first exon of the FMR1 gene which re ...
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Gene therapy: Regulations, ethi ...
Gene therapy is a new and promising approach which opens a new door to the treatment of human diseases. By direct transfer of genetic materials to t ...
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Genomic Organization and Contro ...
Grb7 and their related family members Grb10 and Grb14 are adaptor proteins, which participate in the functionality of multiple signal transduction pa ...
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Comprehensive Resources for Tom ...
Tomato (Solanum lycopersicum L., Solanaceae) is an excellent model plant for genomic research of solanaceous plants, as well as for studying the deve ...
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NBS1 Heterozygosity and Cancer ...
Biallelic mutations in the NBS1 gene are responsible for the Nijmegen breakage syndrome (NBS), a rare autosomal recessive disorder characterized by c ...
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Modeling the Genetic Control of ...
The progression of HIV disease has been markedly slowed by the use of highly active antiretroviral therapy (HAART). However, substantial genetic vari ...
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Haploinsufficiency of DNA Damag ...
Genomic disorders are a clinically diverse group of conditions caused by gain, loss or re-orientation of a genomic region containing dosage-sensitive ...
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On the Epistemological Crisis i ...
There is an epistemological crisis in genomics. At issue is what constitutes scientific knowledge in genomic science, or systems biology in general. ...
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Understanding Genetic Factors i ...
Idiopathic scoliosis (AIS) is the most common pediatric spinal deformity, affecting ~3% of children worldwide. AIS significantly impacts national hea ...
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Meta Analysis of Gene Expressio ...
Since the second half of the 1990s, a large number of genome-wide analyses have been described that study gene expression at the transcript level. To ...
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Molecular Cytogenetics and Cyto ...
Molecular cytogenetics is a promising field of biomedical research that has recently revolutionized our thinking on genome structure and behavior. Th ...
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Episcopic 3D Imaging Methods: T ...
This work aims at describing episcopic 3D imaging methods and at discussing how these methods can contribute to researching the genetic mechanisms dr ...
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