Type 2 Diabetes Mellitus: New Genetic Insights will Lea ...
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Type 2 Diabetes Mellitus: New G ...
Type 2 diabetes is a disorder of dysregulated glucose homeostasis. Normal glucose homeostasis is a complex process involving several interacting mech ...
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New Insights into the Modulatio ...
Fasciola hepatica is a trematode that affects human and domestic ruminant health, causing significant economic losses in cattle estimated at US$2000 ...
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Gene Expression and Regulation ...
Higher plants not only provide human beings renewable food, building materials and energy, but also play the most important role in keeping a stable ...
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Current Screens Based on the Al ...
Global deciphering of signal transduction pathways represents a new challenge of the post-genomic era. However, for the majority of these signaling p ...
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High-Throughput Omics Technolog ...
The mode of action of a huge amount of agents on biological systems is still unknown. One example where more questions than answers exist is covered ...
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Mitochondrial and Nuclear Genes ...
Although the observation of aerobic glycolysis of tumor cells by Otto v. Warburg had demonstrated abnormalities of mitochondrial energy metabolism in ...
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Signaling Transduction Network ...
Nasopharyngeal carcinoma (NPC) is a polygenetic disease. SPLUNC1, UBAP1, BRD7, NAG7, NOR1, NGX6 and LTF genes were found to be tumor suppressor/susce ...
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The Biology of Persistent Infec ...
Multiple Sclerosis (MS) is an immune-mediated demyelinating disease of humans. Although causes of MS are enigmatic, underlying elements contributing ...
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Regulation of Interactions with ...
The molecular machines that replicate the genome consist of many interacting components. Essential to the organization of the replication machinery a ...
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Simultaneous detection of Esche ...
Background: Escherichia coli O157:H7, Vibrio cholerae, and Salmonella typhimurium are pathogenic bacteria found in contaminated water and food. No as ...
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3D QSAR Studies of 1,3,4-oxadia ...
Recently several 1,3,4-oxadiazole derivatives were identified as potentially active antimycobacterial agents. Various 5-aryl-2-thio-1,3,4-oxadiazoles ...
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Mouse Models of Genomic Syndrom ...
Each human's genome is distinguished by extra and missing DNA that can be “benign” or powerfully impact everything from development to disease. In th ...
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Molecular Markers of Tumor Prog ...
Malignant melanoma represents one of the most aggressive malignancies but outcome is highly variable with early tumor lesions having an excellent pro ...
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Living without Oxygen: Anoxia-R ...
Many species of marine mollusks demonstrate exceptional capacities for long term survival without oxygen. Analysis of gene expression under anoxic co ...
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Epigenetic Control of MicroRNA ...
MicroRNAs are a major category among the noncoding RNA fraction that negatively regulate gene expression at the post-transcriptional level, by either ...
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MicroRNA: Implications for Alzh ...
Understanding complex diseases such as sporadic Alzheimer disease (AD) has been a major challenge. Unlike the familial forms of AD, the genetic and e ...
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Beyond Stressed Self: Evidence ...
The activity of cytotoxic lymphocytes is regulated by the opposing function of stimulatory and inhibitory cell surface receptors. According to the no ...
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Estrogen Regulation of MicroRNA ...
Women outlive men, but life expectancy is not influenced by hormone replacement (estrogen + progestin) therapy. Estrogens appear to protect brain, ca ...
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Rallying the Troops: Innate Muc ...
The mucosal surfaces of the gastrointestinal tract are constantly exposed to large quantities of commensal microbes and enteric pathogens. Highly sop ...
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Dendritic Cells and Macrophages ...
Dendritic cells (DCs) and macrophages differently contribute to the generation of coordinated immune system responses against infectious agents. They ...
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The Arrestin Fold: Variations o ...
Endocytosis of ligand-activated plasma membrane receptors has been shown to contribute to the regulation of their downstream signaling. ..-arrestins ...
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Implication of CD154/CD40 Inter ...
The discovery of new functions for CD154 and CD40 molecules has expanded our knowledge to claim that CD154 plays well beyond its postulated role in a ...
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The Story of SPATA2 (Spermatoge ...
In an attempt to isolate new spermatogenesis-associated genes, pd1 was initially identified and cloned as a novel human cDNA sequence from testis cDN ...
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One Decade Later: What has Gene ...
The many diverse functions executed by the central nervous system (CNS) are mirrored in the diverse shapes, connections, and firing patterns of its i ...
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Expression and Function of Krup ...
Krüppel-like factor (KLF) family members share a three C2H2 zinc finger DNA binding domain, and are involved in cell proliferation and differentiatio ...
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