Systems Behavior: Of Male Court ...
Male courtship in fruit flies is regulated by the same major regulatory genes that also determine general sexual differentiation of the animal. Elabo ...
Post-Translational Control of S ...
Sp-family transcription factors are widely expressed in human tissues and involved in the regulation of many cellular processes and response to cellu ...
Functional and Clinical Evidenc ...
We searched for potential suppressors of tumor metastasis by identifying the genes that are frequently down-regulated in hepatocellular carcinomas ( ...
MicroRNA and Cancer: Tiny Molec ...
Cancer is currently a major public health problem and, as such, emerging research is making significant progress in identifying major players in its ...
The Potential Role of Pharmacog ...
Although notable progress has been made in the treatment of non-small-cell lung cancer (NSCLC) in recent years, this disease is still associated with ...
Genome Analysis of Food Grade L ...
Whole-genome sequencing has revolutionized and accelerated scientific research that aims to study the genetics, biochemistry and molecular biology of ...
Plant Spliceosomal Introns: Not ...
Spliceosomal introns in higher eukaryotes are present in a high percentage of protein coding genes and represent a high proportion of transcribed nuc ...
Computational Challenges of Per ...
It is widely predicted that cost and efficiency gains in sequencing will usher in an era of personal genomics and personalized, predictive, preventiv ...
Can Systems Biology Understand ...
Cancer is thought to be caused by a sequence of multiple genetic and epigenetic alterations which occur in one or more of the genes controlling cell ...
Genetic and Molecular Basis of ...
A systematic study has been conducted of all available reports in PubMed and OMIM (Online Mendelian Inheritance in Man) to examine the genetic and mo ...
Clinical Utility of Microarrays ...
Microarray-based clinical tests have become powerful tools in the diagnosis and treatment of diseases. In contrast to traditional DNA-based tests tha ...
Mass Spectrometry-Based Approac ...
Mass spectrometry has served as a major tool for the discipline of proteomics to catalogue proteins in an unprecedented scale. With chemical and meta ...
Cause and Consequences of Genet ...
Both genetic and epigenetic changes contribute to development of human cancer. Oncogenomics has primarily focused on understanding the genetic basis ...
Genetic Variation and Atheroscl ...
A family history of atherosclerosis is independently associated with an increased incidence of cardiovascular events. The genetic factors underlying ...
Oncogenomic Approaches in Explo ...
Cancer is caused by the spatial and temporal accumulation of alterations in the genome of a given cell. This leads to the deregulation of key signall ...
How Drosophila melanogaster For ...
A strictly determined number of external sensory organs, macrochaetes, acting as mechanoreceptors, are orderly located on drosophila head and body. T ...
Gene Polymorphisms and Pharmaco ...
Rheumatoid arthritis (RA) is a systemic, chronic and inflammatory disease of unknown etiology with genetic predisposition. The advent of new biologic ...
Drosophila Lethal Giant Larvae ...
Drosophila lethal giant larvae (lgl) is a tumour suppressor gene whose function in establishing apical-basal cell polarity as well as in exerting pro ...
Genetics and Molecular Biology ...
Tuberous Sclerosis Complex is a multisystem disorder exhibiting a wide range of manifestations characterized by tumour-like lesions called hamartomas ...
Periostin as a Heterofunctional ...
Periostin (Postn) is a heterofunctional secreted extracellular matrix (ECM) protein comprised of four fasciclin domains that promotes cellular adhesi ...
Salivary Genomics, Transcriptom ...
There is an increasingly growing interest world-wide for the genomics, transcriptomics and proteomics of saliva and the oral cavity, since they provi ...
Application of TILLING and EcoT ...
With the fairly recent advent of inexpensive, rapid sequencing technologies that continue to improve sequencing efficiency and accuracy, many species ...
Alternative Splicing and Tumor ...
Alternative splicing is a key molecular mechanism for increasing the functional diversity of the eukaryotic proteomes. A large body of experimental d ...
Analysis of NCL Proteins from a ...
The Neuronal Ceroid Lipofuscinoses (NCLs) are the most common group of neurodegenerative disorders of childhood. While mutations in eight different g ...
Molecular Mechanisms of Inherit ...
Inherited arrhythmias and conduction system diseases are known causes of sudden cardiac death and are responsible for significant mortality and morbi ...