Monoubiquitylation promotes mitochondrial p53 transloc ...
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Monoubiquitylation promotes mit ...
A major function of the p53 tumor suppressor is the induction of a pleiotropic apoptotic program in response to stress through transcription-depende ...
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The Cost of Biopharmaceutical R ...
The costs of developing the types of new drugs that have been pursued by traditional pharmaceutical firms have been estimated in a number of studies. ...
دانلود 3
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Will Medicinal Cannabinoids Pro ...
In some parts of the world, medicinal cannabinoids have already been used to treat nausea and vomiting associated with chemotherapy and wasting in di ...
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Treatment of Chronic Pain with ...
The perception of pain is the result of complicated physiological and psychological processes. Pain can be treated by interrupting peripheral inputs, ...
134.80 KB
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Transdermal Penetration Enhance ...
Transdermal drug therapy has been one of the major research fields in the area of drug therapy for last few decades. However inspite of its large the ...
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Ibopamine Stimulates ..-Adrener ...
Ibopamine stimulates ..-adrenergic receptors and D1-dopaminergic receptors in the eye. Ibopamine is a dopamine analogue and it is hydrolysed to epini ...
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HIV Management: New Approaches
Development of resistance towards currently used anti-HIV drugs is an important determinant in the classical drug failure. Mutations located in the e ...
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Emerging Therapies for Type 2 D ...
Type 2 diabetes results from progressive ..-cell dysfunction and insulin resistance, leading to progressive worsening of glycemic control, and increa ...
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Beta-Blocking Agents and Electr ...
In this review we want to summarize the results of the placebo-controlled randomized clinical trials with betablocking adrenergic agents during elect ...
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Autism Spectrum Disorders: Etio ...
Autism is a complex neurodevelopmental disorder that forms part of a spectrum of related disorders referred to as Autism Spectrum Disorders (ASD). Li ...
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A Review of the Current Role of ...
Proton therapy (PT) is a high-precision form of radiotherapy. The interest in clinical application in oncology of PT is related to its ballistic sele ...
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Properties and Architecture of ...
Computer-based analysis revealed that natural products exhibit a remarkable structural diversity of molecular frameworks and scaffolds that could be ...
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Synthesis of Poison-Frog Alkalo ...
The flexible and efficient enantioselective synthesis of poison-frog alkaloids has been described using the highly stereoselective conjugate addition ...
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Store-Operated Ca2+ Entry in Mu ...
Store-operated Ca2+ entry (SOCE) represents a unique Ca2+ entry mechanism, where Ca2+ channels located on the plasma membrane sense the Ca2+ filling ...
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Structure, Substrate Complexati ...
Asparaginases and glutaminases are enzymes that catalyze the hydrolysis of asparagine or glutamine to the correspondent acid and ammonia. Based on th ...
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Folding, Assembly, and Stabilit ...
Heme cofactors of transmembrane cytochromes are crucial for mediating charge transfer across membranes during aerobic and anaerobic electron transpor ...
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Energy Utilization, Catalysis a ...
Life is fueled by available energy. In fact, life is organized around the utilization of available energy, either from photons or from chemicals. The ...
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Immune Responses to AAV in Clin ...
Recent findings in a clinical trial in which an adeno-associated virus (AAV) vector expressing coagulation factor IX (F.IX) was introduced into the l ...
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Current Advances and Future Cha ...
Gene delivery vectors based on Adenoviral (Ad) vectors have enormous potential for the treatment of both hereditary and acquired disease. Detailed st ...
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Possible Origins of Biohomochir ...
The origin of biohomochirality and the reasons, why this form of homochirality (L-amino acids, D-sugars, etc.) and not the mirror image case was pref ...
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Supramolecularly Organized Lant ...
Using molecular shape for the functional control of multicomponent systems is one of the challenges in the field of supramolecular chemistry. The wel ...
1.16 MB
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New Emergent Nanotechnologies i ...
In this review we explore the advantages deriving from the use of either enzymes or binding proteins to develop non-consuming substrate fluorescence ...
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Quantum Dot Nanocrystals and Su ...
Resonance Energy Transfer (RET) plays an important role, both scientifically and commercially, in diagnostics and high throughput screening. For qual ...
1.21 MB
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Evaluation of Practical Process ...
A few issues to apply Lipozyme TL IM-catalyzed interesterification for bulk fat modification were investigated in a batch reactor system with concern ...
1.90 MB
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A Disposable Electrochemical Gl ...
We report here the development of a novel disposable-type glucose enzyme sensor based on a screen-printed carbon electrode (SPCE) employing a catalyt ...
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