Ethanol Metabolism and Effects: ...
Ethanol (EtOH) in alcoholic beverages is consumed by a large number of individuals and its elimination is primarily by oxidation. The role of nitric ...
The Pharmacokinetics and Pharma ...
Levodopa , a prodrug of dopamine, remains to be one of the main drugs in the treatment of Parkinson’s disease. All current levodopa products are form ...
A New Glucocorticoid Hypothesis ...
The original glucocorticoid (GC) hypothesis of brain aging and Alzheimer’s disease proposed that chronic exposure to GCs promotes hippocampal aging a ...
Nutritional Modulation of Termi ...
Findings with experimental rodent models reveal that exposures to dietary factors during the in utero and pubertal periods when the mammary gland is ...
Mechanism of Action and Potenti ...
“Drinking several cups of green tea a day keeps the doctor away” is clearly an overstatement. However, extensive research has revealed that the predo ...
ECRG1, a novel esophageal gene, ...
ECRG-1 (esophageal cancer-related gene 1) has been previously found to be down-regulated in human esophagus cancer. Transient expression of green fl ...
Dendrimers and Dendritic Polyme ...
Nearly 3 decades ago, a dendritic structure was stepwise synthesized for the first time as a new type of molecules with promising applications. Durin ...
Unique Applications of Novel An ...
Candida albicans is a commensal fungal organism that can over-proliferate and cause disease in the appropriate host setting. C. albicans can cause ir ...
IMGT Colliers de Perles: Standa ...
IMGT®, the international ImMunoGeneTics information system® (http://imgt.cines.fr) provides a common access to expertly annotated data on the genome, ...
Quantum Dot Nanocrystals and Su ...
Resonance Energy Transfer (RET) plays an important role, both scientifically and commercially, in diagnostics and high throughput screening. For qual ...
IMGT Colliers de Perles: Standa ...
IMGT®, the international ImMunoGeneTics information system® (http://imgt.cines.fr) provides a common access to expertly annotated data on the genome, ...
The Phosphoinositide 3-Kinase P ...
The phosphoinositide 3-kinase (PI3K) pathway is frequently activated in human cancer and represents an attractive target for therapies based on small ...
Cutaneous leishmaniasis before ...
Background: Cutaneous leishmaniasis is an endemic infectious disease in Iran caused by flagellated protozoa. The most common cause of cutaneous leish ...
Structural and Functional Deter ...
Alzheimer’s disease is the most common form of neurodegenerative diseases in humans, characterized by the progressive accumulation and aggregation of ...
Advances on the Understanding o ...
Although Alzheimer’s disease (AD) was first discovered a century ago, we are still facing a lack of definitive diagnosis during the patient’s lifetim ...
Genetic Mechanisms and Aberrant ...
Gastric adenocarcinoma occurs via a sequence of molecular events known as the Correa’s Cascade which often progresses over many years. Gastritis, typ ...
The GNAS Locus: Quintessential ...
The currently estimated number of genes in the human genome is much smaller than previously predicted. As an explanation for this disparity, most ind ...
The Basic Biology of BACE1: A K ...
Alzheimer’s disease (AD) is an intractable, neurodegenerative disease that appears to be brought about by both genetic and non-genetic factors. The n ...
HLA Genes in Mayos Population f ...
HLA class I and class II alleles have been studied in 60 unrelated people belonging to Mayos ethnic group, which lives in the Mexican Pacific Sinaloa ...
Validation of Inference Procedu ...
The availability of high-throughput genomic data has motivated the development of numerous algorithms to infer gene regulatory networks. The validity ...
Maps of cis-Regulatory Nodes in ...
The availability of complete human and other metazoan genome sequences has greatly facilitated positioning and analysis of various genomic functional ...
Genetics of Bacterial Alginate: ...
Bacterial alginate genes are chromosomal and fairly widespread among rRNA homology group I Pseudomonads and Azotobacter. In both genera, the genetic ...
The Application of Single Nucle ...
The development of microarray technology has had a significant impact on the genetic analysis of human disease. The recently developed single nucleot ...
EGFR Intron Recombination in Hu ...
The epidermal growth factor receptor (EGFR) is a membrane-bound, 170 kDa, protein tyrosine kinase that plays an important role in tumorigenesis. The ...
EGFR Intron Recombination in Hu ...
The epidermal growth factor receptor (EGFR) is a membrane-bound, 170 kDa, protein tyrosine kinase that plays an important role in tumorigenesis. The ...