p53 mediates the negative regulation of MDM2 by orphan ...
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Amplicons as Vaccine Vectors
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p53 mediates the negative regul ...
MDM2 is an oncoprotein whose transforming potential is activated by overexpression. The expression level of MDM2 is negatively regulated by orphan r ...
582.18 KB
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Production of biopharmaceutical ...
Transgenic plants offer many advantages, including low cost of production (by elimination of fermenters), storage and transportation; heat stability; ...
131.32 KB
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GSK3 at the Edge: Regulation of ...
GSK3 is a multifunctional protein kinase that is pivotal for the regulation of metabolism, the cytoskeleton, and gene expression. Multicellular eukar ...
513.75 KB
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Colloidal and Pharmacological A ...
Human albumin is extensively used and investigated in clinical fluid management. Whether albumin confers sufficient benefit to justify its cost has b ...
485.63 KB
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Cholinergic Treatment of Trauma ...
In spite of affecting the life of millions of people, chronic traumatic brain injury (TBI) has not been hitherto treatable with effective pharmacolog ...
224.09 KB
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Electroporation-Enhanced Nonvir ...
Nonviral gene transfer is markedly enhanced by the application of in vivo electroporation (also denoted electrogene transfer or electrokinetic enhanc ...
249.45 KB
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Amplicons as Vaccine Vectors
HSV-1 amplicon vectors efficiently transduce cultured antigen-presenting cells (APC), including both human and murine dendritic cells as well as prim ...
66.61 KB
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Real Time Single Cell Analysis ...
Bcl-2 homology domain (BH) 3-only proteins couple stress signals to evolutionarily conserved mitochondrial apoptotic pathways. Caspase 8-mediated cl ...
650.70 KB
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Phenotype Data: A Neglected Res ...
To a great extent, our phenotype is determined by our genetic material. Many genotypic modifications may ultimately become manifest in more or less p ...
392.38 KB
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The Role of the COG Database in ...
A major breakthrough in classifying proteins from different microbial genomes in terms of sequence similarity was the development of the COG concept ...
152.48 KB
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OX40:OX40L Axis: Emerging Targe ...
Recent advances in our understanding of the mechanisms through which T cells are activated have led to new therapeutic approaches in the treatment of ...
دانلود 1
152.63 KB
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Accessibility Control of Recomb ...
During B cell development, two somatic DNA recombination events occur at the immunoglobulin heavy chain loci: VDJ recombination and class switch reco ...
503.30 KB
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The Role of the COG Database in ...
A major breakthrough in classifying proteins from different microbial genomes in terms of sequence similarity was the development of the COG concept ...
152.48 KB
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De Novo and Molecular Target-In ...
There is immediate potential to enhance success and innovation in drug development by pairing newly emerging approaches in medicinal chemistry and co ...
217.43 KB
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Liposomal Muramyl Tripeptide Ph ...
About one third of osteosarcoma patients develop lung metastasis refractory to chemotherapy. Recent studies indicate that biological response modifie ...
220.63 KB
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Cholinergic Treatment of Trauma ...
In spite of affecting the life of millions of people, chronic traumatic brain injury (TBI) has not been hitherto treatable with effective pharmacolog ...
224.09 KB
رایگان
Phenotype Data: A Neglected Res ...
To a great extent, our phenotype is determined by our genetic material. Many genotypic modifications may ultimately become manifest in more or less p ...
392.38 KB
رایگان
Colloidal and Pharmacological A ...
Human albumin is extensively used and investigated in clinical fluid management. Whether albumin confers sufficient benefit to justify its cost has b ...
485.63 KB
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Induction of RhoGAP and Patholo ...
Novel experiments with Ultrasound Associated with High Frequency Electromagnetic Field (UAHFEMF) irradiation on rats and mice found evidences of char ...
504.60 KB
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GSK3 at the Edge: Regulation of ...
GSK3 is a multifunctional protein kinase that is pivotal for the regulation of metabolism, the cytoskeleton, and gene expression. Multicellular eukar ...
513.75 KB
رایگان
Ribonucleotide Reductase Inhibi ...
Ribonucleotide reductase (RR) is a multisubunit enzyme responsible for the reduction of ribonucleotides to their corresponding deoxyribonucleotides, ...
524.30 KB
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Bacterial Stationary-State Muta ...
Mechanisms of cellular adaptation may have some commonalities across different organisms. Revealing these common mechanisms may provide insight in th ...
453.55 KB
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Crystal structure of SV40 large ...
The transformation potential of Simian Virus 40 depends on the activities of large T-antigen (LTag), which interacts with several cellular tumor supp ...
841.49 KB
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Phenotype Data: A Neglected Res ...
To a great extent, our phenotype is determined by our genetic material. Many genotypic modifications may ultimately become manifest in more or less p ...
392.38 KB
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Estrogen Signaling Multiple Pat ...
Steroid hormones exert profound effects on cell growth, development, differentiation, and homeostasis. Their effects are mediated through specific in ...
295.71 KB
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