Breast Cancer in the Personal Genomics Era
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Breast Cancer in the Personal G ...
Breast cancer is a heterogeneous disease with a complex etiology that develops from different cellular lineages, progresses along multiple molecular ...
283.54 KB
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Revolver and Superior: Novel Tr ...
High-throughput sequencing of eukaryotic genomes has revived interest in the structure and function of repetitive genomic sequences, previously refer ...
285.16 KB
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Plant Protein-Protein Interacti ...
Protein-protein interaction network represents an important aspect of systems biology. The understanding of the plant proteinprotein interaction netw ...
286.45 KB
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Small RNA Diversity in Plants a ...
MicroRNAs are a class of non-coding RNAs involved in post-transcriptional control of gene expression, either via degradation or translational inhibit ...
291.89 KB
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Estrogen Signaling Multiple Pat ...
Steroid hormones exert profound effects on cell growth, development, differentiation, and homeostasis. Their effects are mediated through specific in ...
295.71 KB
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A General Quantitative Genetic ...
Uncertainty about linkage phases of multiple single nucleotide polymorphisms (SNPs) in heterozygous diploids challenges the identification of specifi ...
295.99 KB
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Causality, Randomness, Intellig ...
Because the basic unit of biology is the cell, biological knowledge is rooted in the epistemology of the cell, and because life is the salient charac ...
296.59 KB
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Consensus Higher Order Repeats ...
Key string algorithm (KSA) could be viewed as robust computational generalization of restriction enzyme method. KSA enables robust and effective iden ...
298.36 KB
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One-Carbon Metabolism and Alzhe ...
Alzheimer’s disease (AD) represents the most common form of dementia in the elderly, characterized by progressive loss of memory and cognitive capaci ...
302.70 KB
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Real-Time PCR: Revolutionizing ...
Invention of polymerase chain reaction (PCR) technology by Kary Mullis in 1984 gave birth to real-time PCR. Real-time..PCR — detection and expression ...
302.82 KB
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An Outbreak of Shigellosis due ...
Background: On June 16 and 17, 2007, the medical clinic of a prison in Isfahan, Iran received multiple reports of gastrointestinal illness among pris ...
100.49 KB
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MDM4 (MDMX) and its Transcript ...
MDM family proteins are crucial regulators of the oncosuppressor p53. Alterations of their gene status, mainly amplification events, have been freque ...
303.08 KB
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Nutrigenomics, ..-Cell Function ...
“Nutrigenomics” refers to the ability of nutrients to alter gene expression. Insulin secreting ک-cells exhibit genomic and molecular changes that enh ...
314.57 KB
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Meiosis-Driven Genome Variation ...
Meiosis includes two successive divisions of the nucleus with one round of DNA replication and leads to the formation of gametes with half of the chr ...
326.00 KB
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Osmoadaptation of Mammalian Cel ...
In mammals, the cells of the renal medulla are physiologically exposed to interstitial osmolalities several-fold higher that found in any other tissu ...
327.83 KB
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5＇–3＇-UTR interactions regulate ...
Optimal induction of p53 protein after DNA damage requires RPL26-mediated increases in p53 mRNA translation. We report here the existence of a dsRNA ...
708.11 KB
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Retinoic Acid Induced 1, RAI1: ...
Genomic structural changes, such as gene Copy Number Variations (CNVs) are extremely abundant in the human genome. An enormous effort is currently on ...
328.94 KB
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Krüppel-Like Factors 4 and 5: U ...
Krüppel-like factors (Klf) 4 and 5 belong to a family of zinc finger-containing transcription factors that share homology with the Drosophila gene Kr ...
330.90 KB
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The HLA Region and Autoimmune D ...
The HLA region encodes several molecules that play key roles in the immune system. Strong association between the HLA region and autoimmune disease ( ...
331.77 KB
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EGFR Intron Recombination in Hu ...
The epidermal growth factor receptor (EGFR) is a membrane-bound, 170 kDa, protein tyrosine kinase that plays an important role in tumorigenesis. The ...
335.14 KB
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EGFR Intron Recombination in Hu ...
The epidermal growth factor receptor (EGFR) is a membrane-bound, 170 kDa, protein tyrosine kinase that plays an important role in tumorigenesis. The ...
335.14 KB
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Glioma oncoprotein Bcl2L12 inhi ...
Glioblastoma multiforme (GBM) is a lethal brain tumor characterized by intense apoptosis resistance and extensive necrosis. Bcl2L12 (for Bcl2-like 12 ...
904.17 KB
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Improvement of Anti-Tumor DNA V ...
DNA vaccine encoding tumor associated antigens (TAAs) is an attractive strategy for tumor vaccine development. But its efficacy to induce efficient a ...
1.01 MB
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The Application of Single Nucle ...
The development of microarray technology has had a significant impact on the genetic analysis of human disease. The recently developed single nucleot ...
340.32 KB
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Genetics of Bacterial Alginate: ...
Bacterial alginate genes are chromosomal and fairly widespread among rRNA homology group I Pseudomonads and Azotobacter. In both genera, the genetic ...
341.41 KB
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