# عنوان نوع فایل سایز فایل بازدید دانلود امتیاز قیمت (تومان)
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Baseline MRI Predictors of Conversion from MCI to Probable AD in the ADNI Cohort
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Involvement of the Toxic AGEs (TAGE)-RAGE System in the Pathogenesis of Diabetic Vascular Complications: A Novel Therapeutic Strategy
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Tumor Systems Need to be Rendered Usable for a New Action-Theoretical Abstraction: The Starting Point for Novel Therapeutic Options
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Classification and Error Estimation for Discrete Data
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Unique Applications of Novel Antifungal Drug Combinations
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Functional Characterization of Chitin and Chitosan
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Activated Protein C and Acute Kidney Injury: Selective Targeting of PAR-1
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Performance of Feature Selection Methods
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Influence of Enzyme-Inducing Antiepileptic Drugs on Trough Level of Imatinib in Glioblastoma Patients
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Serum Serotonin Levels are Associated with Antiviral Therapy Outcomes in Patients with Chronic Hepatitis C
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Targeting Karyotypic Complexity and Chromosomal Instability of Cancer Cells
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Role of Mismatch Repair and MGMT in Response to Anticancer Therapies
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Recent Advances in Intervention in Markovian Regulatory Networks
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Two Diseases with One Hit: Inhibiting a Potential Diabetes Target to Reduce Cancer Risk and to Improve Anti-Cancer Therapy
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Dendrimers and Dendritic Polymers as Anti-infective Agents: New Antimicrobial Strategies for Therapeutic Drugs
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Ribonucleotide Reductase Inhibitors and Future Drug Design
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Development of Non-Nucleoside Reverse Transcriptase Inhibitors for Anti- HIV Therapy
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GSK3 at the Edge: Regulation of Developmental Specification and Cell Polarization
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Induction of RhoGAP and Pathological Changes Characteristic of Alzheimer’s Disease by UAHFEMF Discharge in Rat Brain
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Colloidal and Pharmacological Activity of Albumin in Clinical Fluid Management: Recent Developments
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ECRG1, a novel esophageal gene, cloned and identified from human esophagus and its inhibition effect on tumors
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Pharmacogenomics of Human ABC Transporter ABCC11 (MRP8): Potential Risk of Breast Cancer and Chemotherapy Failure
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Hidden Markov Models and their Applications in Biological Sequence Analysis
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The Protein Kinase Inhibitor Balanol: Structure–Activity Relationships and Structure-Based Computational Studies
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High PIB Retention in Alzheimer’s Disease is an Early Event with Complex Relationship with CSF Biomarkers and Functional Parameters
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Baseline MRI Predictors of Conversion from MCI to Probable AD in the  ADNI Cohort

Baseline MRI Predictors of Conv ...

The Alzheimer’s Disease Neuroimaging Initiative (ADNI) is a multi-center study assessing neuroimaging in diagnosis and longitudinal monitoring. Amnes ...

835.42 KB
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Involvement of the Toxic AGEs (TAGE)-RAGE System in the  Pathogenesis of Diabetic Vascular Complications: A Novel Therapeutic  Strategy

Involvement of the Toxic AGEs ( ...

Diabetic vascular complications are leading causes of acquired blindness, end-stage renal failure, a variety of neuropathies, and accelerated atheros ...

761.27 KB
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Tumor Systems Need to be Rendered Usable for a New Action-Theoretical  Abstraction: The Starting Point for Novel Therapeutic Options

Tumor Systems Need to be Render ...

Background: A tumor system not only consists of diverse cell types but also comprises all components of action insofar that these components are orie ...

752.56 KB
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Classification and Error Estimation for Discrete Data

Classification and Error Estima ...

Discrete classification is common in Genomic Signal Processing applications, in particular in classification of discretized gene expression data, and ...

751.51 KB
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Unique Applications of Novel Antifungal Drug Combinations

Unique Applications of Novel An ...

Candida albicans is a commensal fungal organism that can over-proliferate and cause disease in the appropriate host setting. C. albicans can cause ir ...

683.52 KB
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Functional Characterization of Chitin and Chitosan

Functional Characterization of ...

Chitin and its deacetylated derivative chitosan are natural polymers composed of randomly distributed ..-(1-4)- linked D-glucosamine (deacetylated un ...

682.31 KB
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Activated Protein C and Acute Kidney Injury: Selective Targeting of  PAR-1

Activated Protein C and Acute K ...

Protein C is a plasma serine protease that when activated plays a central role in modulating the function of the vascular endothelium and its interfa ...

655.44 KB
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Performance of Feature Selection Methods

Performance of Feature Selectio ...

High-throughput biological technologies offer the promise of finding feature sets to serve as biomarkers for medical applications; however, the sheer ...

646.88 KB
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Influence of Enzyme-Inducing Antiepileptic Drugs on Trough Level of  Imatinib in Glioblastoma Patients

Influence of Enzyme-Inducing An ...

Background: Imatinib mesylate is used in combination with hydroxyurea (HU) in ongoing clinical phase II studies in recurrent glioblastoma multiforme ...

619.86 KB
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Serum Serotonin Levels are Associated with Antiviral Therapy Outcomes  in Patients with Chronic Hepatitis C

Serum Serotonin Levels are Asso ...

The role of serotonin in contributing to viral clearance has not been investigated in patients with chronic hepatitis C (HCV). In this prospective st ...

1.05 MB
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Targeting Karyotypic Complexity and Chromosomal Instability of Cancer  Cells

Targeting Karyotypic Complexity ...

Multiple karyotypic abnormalities and chromosomal instability are characteristic features of many cancers that are relatively resistant to chemothera ...

591.82 KB
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Role of Mismatch Repair and MGMT in Response to Anticancer Therapies

Role of Mismatch Repair and MGM ...

Tumor resistance to cytotoxic chemotherapy drugs and their toxicity to normal cells are major clinical obstacles to anticancer therapy effectiveness. ...

566.00 KB
رایگان
Recent Advances in Intervention in Markovian Regulatory Networks

Recent Advances in Intervention ...

Markovian regulatory networks constitute a class of discrete state-space models used to study gene regulatory dynamics and discover methods that bene ...

557.72 KB
رایگان
Two Diseases with One Hit: Inhibiting a Potential Diabetes Target to  Reduce Cancer Risk and to Improve Anti-Cancer Therapy

Two Diseases with One Hit: Inhi ...

Obesity is a well-recognized cancer risk factor. The increase in risk for colorectal, endometrial, breast and esophageal cancers associated with obes ...

548.47 KB
رایگان
Dendrimers and Dendritic Polymers as Anti-infective Agents: New Antimicrobial  Strategies for Therapeutic Drugs

Dendrimers and Dendritic Polyme ...

Nearly 3 decades ago, a dendritic structure was stepwise synthesized for the first time as a new type of molecules with promising applications. Durin ...

دانلود 1
535.96 KB
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Ribonucleotide Reductase Inhibitors and Future Drug Design

Ribonucleotide Reductase Inhibi ...

Ribonucleotide reductase (RR) is a multisubunit enzyme responsible for the reduction of ribonucleotides to their corresponding deoxyribonucleotides, ...

524.30 KB
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Development of Non-Nucleoside Reverse Transcriptase Inhibitors for Anti-  HIV Therapy

Development of Non-Nucleoside R ...

The NNRTIs play an important role in the present therapy against HIV/AIDS. This review discusses the basic principles in the development of NNRTIs fo ...

514.76 KB
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GSK3 at the Edge: Regulation of Developmental Specification and Cell Polarization

GSK3 at the Edge: Regulation of ...

GSK3 is a multifunctional protein kinase that is pivotal for the regulation of metabolism, the cytoskeleton, and gene expression. Multicellular eukar ...

513.75 KB
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Induction of RhoGAP and Pathological Changes Characteristic of Alzheimer’s  Disease by UAHFEMF Discharge in Rat Brain

Induction of RhoGAP and Patholo ...

Novel experiments with Ultrasound Associated with High Frequency Electromagnetic Field (UAHFEMF) irradiation on rats and mice found evidences of char ...

دانلود 1
504.60 KB
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Colloidal and Pharmacological Activity of Albumin in Clinical Fluid Management:  Recent Developments

Colloidal and Pharmacological A ...

Human albumin is extensively used and investigated in clinical fluid management. Whether albumin confers sufficient benefit to justify its cost has b ...

485.63 KB
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ECRG1, a novel esophageal gene, cloned and identified from human esophagus and its  inhibition effect on tumors

ECRG1, a novel esophageal gene, ...

ECRG-1 (esophageal cancer-related gene 1) has been previously found to be down-regulated in human esophagus cancer. Transient expression of green fl ...

310.00 KB
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Pharmacogenomics of Human ABC Transporter ABCC11 (MRP8): Potential Risk of  Breast Cancer and Chemotherapy Failure

Pharmacogenomics of Human ABC T ...

Some genetic polymorphisms of human ABC transporter genes are reportedly related to the risk of certain diseases and patients’ responses to medicatio ...

466.79 KB
رایگان
Hidden Markov Models and their Applications in Biological Sequence  Analysis

Hidden Markov Models and their ...

Hidden Markov models (HMMs) have been extensively used in biological sequence analysis. In this paper, we give a tutorial review of HMMs and their ap ...

443.46 KB
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The Protein Kinase Inhibitor Balanol: Structure–Activity Relationships and  Structure-Based Computational Studies

The Protein Kinase Inhibitor Ba ...

Balanol, a fungal metabolite, is a potent ATP-competitive inhibitor of Protein Kinase C (PKC) and Protein Kinase A (PKA), important targets in oncolo ...

441.77 KB
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High PIB Retention in Alzheimer’s Disease is an Early Event with Complex  Relationship with CSF Biomarkers and Functional Parameters

High PIB Retention in Alzheimer ...

Background: New in vivo amyloid PET imaging tracers, such as 11C-PIB, provide possibilities to deeper understand the underlying pathological processe ...

437.30 KB
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