Baseline MRI Predictors of Conv ...
The Alzheimer’s Disease Neuroimaging Initiative (ADNI) is a multi-center study assessing neuroimaging in diagnosis and longitudinal monitoring. Amnes ...
Involvement of the Toxic AGEs ( ...
Diabetic vascular complications are leading causes of acquired blindness, end-stage renal failure, a variety of neuropathies, and accelerated atheros ...
Tumor Systems Need to be Render ...
Background: A tumor system not only consists of diverse cell types but also comprises all components of action insofar that these components are orie ...
Classification and Error Estima ...
Discrete classification is common in Genomic Signal Processing applications, in particular in classification of discretized gene expression data, and ...
Unique Applications of Novel An ...
Candida albicans is a commensal fungal organism that can over-proliferate and cause disease in the appropriate host setting. C. albicans can cause ir ...
Functional Characterization of ...
Chitin and its deacetylated derivative chitosan are natural polymers composed of randomly distributed ..-(1-4)- linked D-glucosamine (deacetylated un ...
Activated Protein C and Acute K ...
Protein C is a plasma serine protease that when activated plays a central role in modulating the function of the vascular endothelium and its interfa ...
Performance of Feature Selectio ...
High-throughput biological technologies offer the promise of finding feature sets to serve as biomarkers for medical applications; however, the sheer ...
Influence of Enzyme-Inducing An ...
Background: Imatinib mesylate is used in combination with hydroxyurea (HU) in ongoing clinical phase II studies in recurrent glioblastoma multiforme ...
Serum Serotonin Levels are Asso ...
The role of serotonin in contributing to viral clearance has not been investigated in patients with chronic hepatitis C (HCV). In this prospective st ...
Targeting Karyotypic Complexity ...
Multiple karyotypic abnormalities and chromosomal instability are characteristic features of many cancers that are relatively resistant to chemothera ...
Role of Mismatch Repair and MGM ...
Tumor resistance to cytotoxic chemotherapy drugs and their toxicity to normal cells are major clinical obstacles to anticancer therapy effectiveness. ...
Recent Advances in Intervention ...
Markovian regulatory networks constitute a class of discrete state-space models used to study gene regulatory dynamics and discover methods that bene ...
Two Diseases with One Hit: Inhi ...
Obesity is a well-recognized cancer risk factor. The increase in risk for colorectal, endometrial, breast and esophageal cancers associated with obes ...
Dendrimers and Dendritic Polyme ...
Nearly 3 decades ago, a dendritic structure was stepwise synthesized for the first time as a new type of molecules with promising applications. Durin ...
Ribonucleotide Reductase Inhibi ...
Ribonucleotide reductase (RR) is a multisubunit enzyme responsible for the reduction of ribonucleotides to their corresponding deoxyribonucleotides, ...
Development of Non-Nucleoside R ...
The NNRTIs play an important role in the present therapy against HIV/AIDS. This review discusses the basic principles in the development of NNRTIs fo ...
GSK3 at the Edge: Regulation of ...
GSK3 is a multifunctional protein kinase that is pivotal for the regulation of metabolism, the cytoskeleton, and gene expression. Multicellular eukar ...
Induction of RhoGAP and Patholo ...
Novel experiments with Ultrasound Associated with High Frequency Electromagnetic Field (UAHFEMF) irradiation on rats and mice found evidences of char ...
Colloidal and Pharmacological A ...
Human albumin is extensively used and investigated in clinical fluid management. Whether albumin confers sufficient benefit to justify its cost has b ...
ECRG1, a novel esophageal gene, ...
ECRG-1 (esophageal cancer-related gene 1) has been previously found to be down-regulated in human esophagus cancer. Transient expression of green fl ...
Pharmacogenomics of Human ABC T ...
Some genetic polymorphisms of human ABC transporter genes are reportedly related to the risk of certain diseases and patients’ responses to medicatio ...
Hidden Markov Models and their ...
Hidden Markov models (HMMs) have been extensively used in biological sequence analysis. In this paper, we give a tutorial review of HMMs and their ap ...
The Protein Kinase Inhibitor Ba ...
Balanol, a fungal metabolite, is a potent ATP-competitive inhibitor of Protein Kinase C (PKC) and Protein Kinase A (PKA), important targets in oncolo ...
High PIB Retention in Alzheimer ...
Background: New in vivo amyloid PET imaging tracers, such as 11C-PIB, provide possibilities to deeper understand the underlying pathological processe ...