Strategies for Overcoming Inherent and Acquired Resista ...
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Cause of Chirality Consensus
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Strategies for Overcoming Inher ...
Mutations in K-Ras are observed in approximately 40% of colon tumours. This has significant implications for predicting likelihood of response to the ...
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Recent Methods in Antimalarial ...
As malaria continues to be a worldwide problem due to increasing drug resistance, several drug susceptibility techniques have been reported in the li ...
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Natural Non-Trasgenic Animal Mo ...
The most common animal models currently used for Alzheimer disease (AD) research are transgenic mice that express a mutant form of human A.. precurso ...
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A New Glucocorticoid Hypothesis ...
The original glucocorticoid (GC) hypothesis of brain aging and Alzheimer’s disease proposed that chronic exposure to GCs promotes hippocampal aging a ...
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Optimised electroporation media ...
Background: Immunological therapies enhance the ability of the immune system to recognise and destroy cancer cells via selective killing mechanisms. ...
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Cause of Chirality Consensus
Biological macromolecules, proteins and nucleic acids are composed exclusively of chirally pure monomers. The chirality consensus appears vital for l ...
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The Pharmacokinetics and Pharma ...
Levodopa , a prodrug of dopamine, remains to be one of the main drugs in the treatment of Parkinson’s disease. All current levodopa products are form ...
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Cholinergic Treatment of Trauma ...
In spite of affecting the life of millions of people, chronic traumatic brain injury (TBI) has not been hitherto treatable with effective pharmacolog ...
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Liposomal Muramyl Tripeptide Ph ...
About one third of osteosarcoma patients develop lung metastasis refractory to chemotherapy. Recent studies indicate that biological response modifie ...
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De Novo and Molecular Target-In ...
There is immediate potential to enhance success and innovation in drug development by pairing newly emerging approaches in medicinal chemistry and co ...
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Computational Approaches for Pr ...
A central focus of cancer genetics is the study of mutations that are causally implicated in tumorigenesis. Although missense variants are commonly i ...
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Depression and Quality of Life ...
Diabetes patients are known to have a worse quality of life than individuals without diabetes. They also have an increased risk for depressive sympto ...
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Ethanol Metabolism and Effects: ...
Ethanol (EtOH) in alcoholic beverages is consumed by a large number of individuals and its elimination is primarily by oxidation. The role of nitric ...
دانلود 1
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Long-Term Follow-Up of Patients ...
Background: Immunization of patients with Alzheimer’s disease (AD) with synthetic amyloid-.. peptide (A..42) (AN1792) was previously studied in a ran ...
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The Role of the COG Database in ...
A major breakthrough in classifying proteins from different microbial genomes in terms of sequence similarity was the development of the COG concept ...
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A single dose of DNA vaccine ba ...
Background: Highly pathogenic avian influenza virus subtype H5N1 infects humans with a high fatality rate and has pandemic potential. Vaccination is ...
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Atherosclerosis and Arterial Bl ...
Increased blood pressure is a consistent risk factor for the development of atherosclerotic diseases in humans, although the basis for this relations ...
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Expression and Function of Krup ...
Krüppel-like factor (KLF) family members share a three C2H2 zinc finger DNA binding domain, and are involved in cell proliferation and differentiatio ...
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One Decade Later: What has Gene ...
The many diverse functions executed by the central nervous system (CNS) are mirrored in the diverse shapes, connections, and firing patterns of its i ...
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Regulation of the Endoplasmic R ...
Calcium is a ubiquitous second messenger and is involved in virtually all cellular functions. Cellular events being regulated by calcium include gene ...
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Mechanisms Used by Human Papill ...
The greatest risk factor for the development of cervical and other cancers that have been linked to the human papillomavirus (HPV) family is the pers ...
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The Story of SPATA2 (Spermatoge ...
In an attempt to isolate new spermatogenesis-associated genes, pd1 was initially identified and cloned as a novel human cDNA sequence from testis cDN ...
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MicroRNA: Biogenesis, Function ...
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the regulation of gene expression. MicroRNAs are transcribed by RNA polyme ...
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Multiple Hsp70 Isoforms in the ...
Hsp70 molecular chaperones play a variety of functions in every organism, cell type and organelle, and their activities have been implicated in a num ...
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Implication of CD154/CD40 Inter ...
The discovery of new functions for CD154 and CD40 molecules has expanded our knowledge to claim that CD154 plays well beyond its postulated role in a ...
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