Gene Therapy Targeting Nuclear Factor-ƘB: Towards Clini ...
رایگان
Gene Therapy Targeting Nuclear ...
Nuclear factor (NF)-..B is regarded as one of the most important transcription factors and plays an essential role in the transcriptional activation ...
267.77 KB
رایگان
Reduction of enterotoxigenic Es ...
The aim of this study was to examine the reduction of enterotoxigenic Escherichia coli (ETEC) colonization by oral administration of Lactobacillus ca ...
202.01 KB
رایگان
State-of-the-Art Lentiviral Vec ...
Lentiviral vectors (LV) are competent gene transfer vehicles, as used for both research and gene therapy applications, because of their stable integr ...
277.85 KB
رایگان
Copper, An Ancient Remedy Retur ...
Copper has potent biocidal properties. Copper ions, either alone or in copper complexes, have been used for centuries to disinfect liquids, solids an ...
165.05 KB
رایگان
Supramolecularly Organized Lant ...
Using molecular shape for the functional control of multicomponent systems is one of the challenges in the field of supramolecular chemistry. The wel ...
1.16 MB
رایگان
Molecular Kinetics and Targetin ...
Protein mobility, chromatin movement and the formation of molecular assemblies in the cell nucleus have, until fairly recently, been viewed in a pseu ...
777.61 KB
رایگان
Real Time Single Cell Analysis ...
Bcl-2 homology domain (BH) 3-only proteins couple stress signals to evolutionarily conserved mitochondrial apoptotic pathways. Caspase 8-mediated cl ...
650.70 KB
رایگان
Manufacturing and Regulatory St ...
Recombinant adeno-associated virus (AAV) -based vectors expressing therapeutic gene products have shown great promise for human gene therapy. A recen ...
دانلود 1
301.23 KB
رایگان
Meganucleases and Other Tools f ...
The importance of safer approaches for gene therapy has been underscored by a series of severe adverse events (SAEs) observed in patients involved in ...
542.06 KB
رایگان
Cause of Chirality Consensus
Biological macromolecules, proteins and nucleic acids are composed exclusively of chirally pure monomers. The chirality consensus appears vital for l ...
231.92 KB
رایگان
Amplicons as Vaccine Vectors
HSV-1 amplicon vectors efficiently transduce cultured antigen-presenting cells (APC), including both human and murine dendritic cells as well as prim ...
66.61 KB
رایگان
Regulation of Catalysis Within ...
Enzymes are catalysts adapted to function in biological systems. This review shows how chemical processes contribute to the adaptations. The catalyst ...
237.72 KB
رایگان
Enzymes with Phosphotriesterase ...
Organophosphates (OPs) are a class of synthetic compounds used both as pesticides and nerve agents. They are chemically phosphoesters and biologicall ...
536.14 KB
رایگان
Haploview: analysis and visuali ...
Research over the last few years has revealed significant haplotype structure in the human genome. The characterization of these patterns, particula ...
دانلود 5
135.63 KB
رایگان
Possible Origins of Biohomochir ...
The origin of biohomochirality and the reasons, why this form of homochirality (L-amino acids, D-sugars, etc.) and not the mirror image case was pref ...
336.25 KB
رایگان
Current Advances and Future Cha ...
Gene delivery vectors based on Adenoviral (Ad) vectors have enormous potential for the treatment of both hereditary and acquired disease. Detailed st ...
377.66 KB
رایگان
Immune Responses to AAV in Clin ...
Recent findings in a clinical trial in which an adeno-associated virus (AAV) vector expressing coagulation factor IX (F.IX) was introduced into the l ...
153.91 KB
رایگان
Functional Characterization of ...
Chitin and its deacetylated derivative chitosan are natural polymers composed of randomly distributed ..-(1-4)- linked D-glucosamine (deacetylated un ...
682.31 KB
رایگان
Energy Utilization, Catalysis a ...
Life is fueled by available energy. In fact, life is organized around the utilization of available energy, either from photons or from chemicals. The ...
85.98 KB
رایگان
N-Terminal Specific Fluorescenc ...
The function of a protein correlates closely with its structure; even partial structural disorder/misfolding may lead to various diseases such as Par ...
780.55 KB
رایگان
Microfluidic Bioreactors for Hi ...
Protein digestion is a key procedure prior to mass spectrometry identification in proteome research. During the past decade, a variety of microfluidi ...
437.91 KB
رایگان
Gene Electrotransfer to Skin; R ...
Gene electrotransfer, which designates the combination of gene transfer and electroporation, is a non-viral means for transfecting genes into cells a ...
227.99 KB
رایگان
Gene Electrotransfer to Skin; R ...
Gene electrotransfer, which designates the combination of gene transfer and electroporation, is a non-viral means for transfecting genes into cells a ...
227.99 KB
رایگان
Evaluation of Angiogenesis with ...
Background: The most potent angiogenic factor is the vascular endothelial growth factor (VEGF), and CD34 is an endothelial antigen that has been used ...
75.69 KB
رایگان
Cloning and expression of a reg ...
An assay for the endopeptidase activities of clostridial neurotoxins in contaminated biotherapeutic products has been developed. Based on a synthetic ...
575.66 KB
رایگان
