Treatment of Chronic Pain with ...
The perception of pain is the result of complicated physiological and psychological processes. Pain can be treated by interrupting peripheral inputs, ...
Update on Antifolate Drugs Targ ...
Antifolate drugs are molecules directed to interfere with the folate metabolic pathway at some level. They can be recognized among the first rational ...
Who’s Winning the War? Molecula ...
The ability of clinicians to wage an effective war against many bacterial infections is increasingly being hampered by skyrocketing rates of antibiot ...
Will Medicinal Cannabinoids Pro ...
In some parts of the world, medicinal cannabinoids have already been used to treat nausea and vomiting associated with chemotherapy and wasting in di ...
Evaluation of lymph node number ...
Background: Although evaluation of at least 12 lymph nodes (LNs) is recommended as the minimum number of nodes required for accurate staging of colon ...
Genomic characterization of the ...
Background: Mitochondrial tumor suppressor gene 1 (MTUS1) has been recently identified as a candidate tumor suppressor gene which resides in a genomi ...
Production of biopharmaceutical ...
Transgenic plants offer many advantages, including low cost of production (by elimination of fermenters), storage and transportation; heat stability; ...
Fine mapping the TAGAP risk loc ...
A common allele at the TAGAP gene locus demonstrates a suggestive, but not conclusive association with risk of rheumatoid arthritis (RA). To fine map ...
Fine mapping the TAGAP risk loc ...
A common allele at the TAGAP gene locus demonstrates a suggestive, but not conclusive association with risk of rheumatoid arthritis (RA). To fine map ...
Fine mapping the TAGAP risk loc ...
A common allele at the TAGAP gene locus demonstrates a suggestive, but not conclusive association with risk of rheumatoid arthritis (RA). To fine map ...
GENE THERAPY: ETHICAL AND SOCIA ...
Many diseases are genetically determined; for example, Huntington’s disease and cystic fibrosis (CF). Others are influenced by genes, but involve add ...
The Cost of Biopharmaceutical R ...
The costs of developing the types of new drugs that have been pursued by traditional pharmaceutical firms have been estimated in a number of studies. ...
Cytokine profiles and phenotype ...
The present study examined the immunological response of antigen presenting cells (APC) to genotype-I isolates of porcine reproductive and respirator ...
Harnessing Dendritic Cells for ...
Abstract: Dendritic cells (DC) are professional antigen presenting cells that are crucial for the induction of anti-tumor T cell responses. As a conse ...
Antigen presentation in EAE: ro ...
Experimental autoimmune encephalomyelitis (EAE), a well-established model of multiple sclerosis, is characterised by microglial activation and lymph ...
Harnessing Dendritic Cells for ...
Abstract: Dendritic cells (DC) are professional antigen presenting cells that are crucial for the induction of anti-tumor T cell responses. As a conse ...
Systematic Review on the Effica ...
Evidence-based medicine represents the effort to highlight the best intervention for patients, clinicians, and policy makers, each from their respec ...
Evidence for Clinical Safety, E ...
Allergic rhinitis (AR) and chronic idiopathic urticaria (CIU) are highly burdensome diseases, which are increasing in prevalence, especially in the ...
Hypersensitivity Reactions to C ...
Background: Hypersensitivity to contrast media (CMs) may be common and serious. Aim: To evaluate the prevalence of CM hypersensitivity, risk factors ...
Common Variable Immunodeficienc ...
One of the great advances in clinical medicine was the recognition of the pleomorphism of the immune response and the multiple afferent and efferent ...
Flagellin Induces the Expressio ...
Background: Thymic stromal lymphopoietin (TSLP), highly expressed by keratinocytes in skin lesions of atopic dermatitis patients and bronchial epith ...
Possible Association of SLC22A2 ...
Background: Aspirin-intolerant asthma (AIA) is a clinical syndrome characterized by acute bronchoconstriction following the ingestion of aspirin. So ...
A Toll-Like Receptor 2/6 Agonis ...
Background: The hygiene hypothesis negatively correlates the microbial burden of the environment with the prevalence of T helper type 2 (Th2)-relate ...
The Role of the House Dust Mite ...
House dust mite (HDM) represents one of the most common sources of aeroallergens worldwide and more than 50% of allergic patients are sensitized to ...
Th17 Immunity in Patients with ...
Background: Allergic asthma is an inflammatory disease regulated by the T helper (Th) cells. The Th1/Th2 imbalance has been well documented in the p ...