Disposition of quinine and its major metabolite, 3- hyd ...
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Gene therapy
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Disposition of quinine and its ...
Quinine, extensively metabolized by CYP 3A4, has 3-hydroxyquinine as the major metabolite which also contributes to its antimalarial activity. This s ...
78.97 KB
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Effects and mechanism of action ...
While hepatic schistosomiasis results in morbidity from infection and complications of liver fibrosis, there are few medicines/means available to pre ...
1.41 MB
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Antinociceptive potential of th ...
This study investigated the antinociceptive effects of the methanolic extract of the stem wood of Microdermis puberula (Hook. F. Ex. Planch) in Swiss ...
دانلود 3
54.44 KB
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Antinociceptive potential of th ...
This study investigated the antinociceptive effects of the methanolic extract of the stem wood of Microdermis puberula (Hook. F. Ex. Planch) in Swiss ...
دانلود 4
54.44 KB
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Effect of EDTA on the activity ...
Ethylenediamine Tetraacetic Acid (EDTA) is a compound predominantly known for its chelating ability. It has also been found that in combination with ...
52.75 KB
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Discovery and Development of An ...
The unmet need for effective antivirals against potential agents of bioterrorism and emerging infections is obvious; however, the challenges to devel ...
44.11 KB
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The NewWorld of Biosimilars:Wha ...
Biosimilar pharmaceuticals are emerging as patent protection on the original biopharmaceutical products expires. However, biopharmaceuticals are part ...
892.06 KB
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Antifungal activity of aqueous ...
Aqueous and ethanolic extracts of Picralima nitida seeds were tested for their antifungal activities using Aspergillus flavus, Candida albicans and M ...
63.21 KB
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Antifungal activity of aqueous ...
Aqueous and ethanolic extracts of Picralima nitida seeds were tested for their antifungal activities using Aspergillus flavus, Candida albicans and M ...
63.21 KB
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The Cost of Biopharmaceutical R ...
The costs of developing the types of new drugs that have been pursued by traditional pharmaceutical firms have been estimated in a number of studies. ...
158.09 KB
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Echium acanthocarpum hairy root ...
Background The therapeutic and health promoting role of highly unsaturated fatty acids (HUFAs) from fish, i.e. eicosapentaenoic acid (EPA, 20:5n-3) ...
498.19 KB
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Estimation of affinities of lig ...
Background: The combinatorial library strategy of using multiple candidate ligands in mixtures as library members is ideal in terms of cost and effic ...
1.42 MB
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Proteomics to study genes and g ...
Proteomics, the large-scale analysis of proteins, will contribute greatly to our understanding of gene function in the post-genomic era. Proteomics c ...
466.79 KB
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Proteomics: new perspectives, n ...
Proteomics-based approaches, which examine the expressed proteins of a tissue or cell type, complement the genome initiatives and are increasingly be ...
3.17 MB
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Proteomics: translating genomic ...
By cataloging the entire protein content of a cell, proteomics should not only provide insight into the molecular basis of life, but also accelerate ...
256.18 KB
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A Biological Atlas of Functiona ...
The availability of complete genome sequences for humap is usually sufficient to find the way. However for man and other organisms is expected to ch ...
460.86 KB
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Proteomics: an evolving technol ...
The rapid developments in both genomics and proteomics will allow scientists to define the molecular pathways in normal and diseased cells. With the ...
191.37 KB
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Gene therapy
In recent years, there have been a number of technological breakthroughs that have allowed for clinical trials in gene therapy to be initiated. In c ...
135.78 KB
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Fibroblast Growth Factor-2 and ...
Bone marrow mesenchymal stem cells (BMMSCs) have the capacity for self-renewal, and differentiation into a variety of cell types. They thus represent ...
504.03 KB
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1,2-propanediol-trehalose mixtu ...
Background: Quantitative real-time PCR (qPCR) is becoming increasingly important for DNA genotyping and gene expression analysis. For continuous moni ...
1.27 MB
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mRNA transcript quantification ...
Background: A recently developed probe-based technology, the NanoString nCounter™ gene expression system, has been shown to allow accurate mRNA trans ...
1.20 MB
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Molecular characterization of f ...
Substantial fraction of information has been added with reference to fusion transcripts in hematological malignancies. However these fusion transcrip ...
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Database resources of the Natio ...
In addition to maintaining the GenBank nucleic acid sequence database, the National Center for Biotechnology Information (NCBI) provides analysis ...
107.10 KB
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Molecular variants of Bardet-Bi ...
Bardet-Biedl Syndrome (BBS) is a genetically and clinically heterogeneous disorder clinically characterized by obesity, mental retardation, dysphormi ...
166.28 KB
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Proliferation of Juglans regia ...
One of the new and important ways of plant propagation is micropropagation or tissue culture technique. Using this technique is preferred due to its ...
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