Glutathione S- transferase M1 and T1 gene polymorphisms ...
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Glutathione S- transferase M1 a ...
Stroke is a multifactorial disease caused by the interaction of several genetic and environmental factors and a variety of risk factors such as blood ...
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Evidence of association of a co ...
Genetic variants of endothelial nitric oxide synthase (eNOS) could influence individual susceptibility to coronary artery disease (CAD) with or witho ...
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A New Human Somatic Stem Cell f ...
Here a new, intrinsically pluripotent, CD45-negative population from human cord blood, termed unrestricted somatic stem cells (USSCs) is described. T ...
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EMBRYONIC STEM CELLS/INDUCED PL ...
Human pluripotent stem cells from embryonic origins and those generated from reprogrammed somatic cells share many characteristics, including indefi ...
1.03 MB
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Different populations and sourc ...
The mesenchymal stroma harbors an important population of cells that possess stem cell-like characteristics including self renewal and differentiatio ...
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Induction of Pluripotent Stem C ...
Successful reprogramming of differentiated human somatic cells into a pluripotent state would allow creation of patient- and disease-specific stem ...
2.03 MB
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In vitro derivation of function ...
The capacity for self-renewal and differentiation of human embryonic stem (ES) cells makes them a potential source for generation of pancreatic beta ...
1.34 MB
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Functional Module Analysis Reve ...
Mesenchymal stem cells (MSCs) found in bone marrow (BM)-MSCs are an attractive source for the regeneration of damaged tissues. Alternative postnatal, ...
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Constitutive Gs activation usin ...
Introduction: The controlled expression of many genes, including G-protein coupled receptors (GPCRs), is important for delineating gene functions in ...
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Lentiviral vector mediated modi ...
Introduction: A combination of gene and cell therapies has the potential to significantly enhance the therapeutic value of mesenchymal stem cells (MS ...
659.00 KB
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Efficient co-expression of bici ...
Introduction: Local synthesis of interferon within B16 tumors mediates anti-tumor effects. Based on reports that stem cells are recruited to tumors, ...
3.57 MB
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Stimulation of Activin A/Nodal ...
Introduction: Unrestricted somatic stem cells (USSC) derived from umbilical cord blood are an attractive alternative to human embryonic stem cells (h ...
3.50 MB
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Gene expression changes with di ...
Introduction Owing to wide availability, low cost and avoidance of ethical concerns, umbilical cord blood (UCB) provides an attractive source of ste ...
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Human multipotent stromal cells ...
Introduction: Multipotent stromal cells (MSCs) are currently in clinical trials for a number of inflammatory diseases. Recent studies have demonstrat ...
8.17 MB
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Cloning, Expression, Purificati ...
Through alternative promoter usage, human retinoblastoma protein-interacting zinc finger gene RIZ encodes two different protein products, RIZ1 and RI ...
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Stem Cell Research & Therap ...
Just over a year ago we launched Stem Cell Research & Th erapy with the aim of it becoming the major forum for translational research into stem cell ...
128.07 KB
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MDM2 antagonist Nutlin-3a poten ...
Background: Frequent failure and severe side effects of current sarcoma therapy warrants new therapeutic approaches. The small-molecule MDM2 antagon ...
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Cell-free synthesis of a functi ...
Background: G protein coupled receptors (GPCRs) represent the largest family of membrane proteins in the human genome and the richest source of targe ...
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Future of cord blood for non-on ...
For the last 5 years cord blood (CB) has been under intense experimental investigation in in vitro differentiation models and in preclinical animal ...
1,006.88 KB
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A visual method for direct sele ...
Background: The methylotrophic yeast, Pichia pastoris, offers the possibility to generate a high amount of recombinant proteins in a fast and easy wa ...
1.37 MB
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Improved mycobacterial protein ...
Background: The non-pathogenic bacterium Mycobacterium smegmatis is widely used as a near-native expression host for the purification of Mycobacteriu ...
1.37 MB
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Supramolecular assemblies of ri ...
Background: Cationic bilayers based on the inexpensive synthetic lipid dioctadecyldimethylammonium bromide (DODAB) have been useful as carriers for d ...
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Construction of high quality Ga ...
Background Monocots, especially the temperate grasses, represent some of the most agriculturally important crops for both current food needs and fut ...
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Defective Interfering Virus Pro ...
Background. We have identified and characterised a defective-interfering (DI) influenza A virus particles containing a highly deleted segment 1 RNA t ...
1.72 MB
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Direct antiglobulin test (Coomb ...
Primary Epstein-Barr virus infection in children is usually asymptomatic, but some children or young adults manifest infectious mononucleosis with ty ...
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