MIB1/Ki-67 labelling index can classify grade 2 breast ...
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Vascular Access in Children
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MIB1/Ki-67 labelling index can ...
Histological grade is recognized as one of the strongest prognostic factors in operable breast cancer (BC). Although grade 1 and grade 3 tumours are ...
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Clinical significance of sentin ...
The advent of sentinel lymph node biopsy (SLNB) and improvements in histopathological and molecular analysis have increased the rate at which isolat ...
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A systematic review of the rela ...
The estrogen signal is mediated by the estrogen receptor (ER). The specific role of ER-beta, a second ER, in breast carcinogenesis is not known. A n ...
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High-resolution analyses of gen ...
The advent of high-throughput technologies in molecular biology has dramatically increased our understanding of breast cancer during the past decade ...
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The liver receptor homolog-1 re ...
Estrogen receptor-a (ER) is expressed in the great majority of breast cancers, and the inhibition of ER action is a key part of breast cancer treatm ...
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Targeting trastuzumab-resistant ...
Targeting HER-2 over-expressing breast cancer cells with trastuzumab has resulted in significant improvements in both disease-free and overall survi ...
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Nuclear and cytoplasmic express ...
Estrogen receptor (ER) a has been studied extensively in familial breast cancers but there are limited data on ERb and its isoforms. This is an impo ...
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Docetaxel metabolism is not alt ...
Docetaxel is primarily metabolized by CYP3A4 and susceptible to alterations in clearance by CYP3A4 inhibition and induction. Imatinib is a CYP3A4 in ...
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The association between vascula ...
Vascular endothelial growth factor (VEGF) is important in breast carcinogenesis. However, whether the effect of VEGF expression on survival varies w ...
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Mutations in BRCA2 and PALB2 in ...
Male breast cancer (MBC) is an uncommon disease with a frequency of approximately one in 1000. Due to the rarity of MBC, it is understudied and its ...
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Mutation analysis of RAD51L1 (R ...
Although a significant proportion of familial aggregation of breast cancer remains unexplained, many of the currently known breast cancer susceptibi ...
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Five-year patterns of adjuvant ...
Adjuvant hormonal therapy (HT) for breast cancer improves survival, yet studies have shown that early discontinuation and suboptimal adherence are c ...
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Elimination of the chemotherapy ...
Metastatic breast cancer is currently incurable despite initial responsiveness, assumingly due to the presence of chemoresistant subpopulations that ...
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Primary tumor classification ac ...
Breast cancer patients with similar clinical stage may experience different disease outcomes. Aberrant DNA methylation of primary breast tumors can ...
565.85 KB
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Androgens and musculoskeletal s ...
Aromatase inhibitors (AIs), the adjuvant hormonal treatment of choice for postmenopausal estrogen receptor-positive breast cancer, are associated wi ...
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Parity and breastfeeding are pr ...
Background Breast cancer (BC) is the most prevalent cancer in Iranian women and the fifth most common cause of cancer-related death in Iran. Among p ...
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Quantitative prediction of tumo ...
Background In breast cancer, the identification of accurate predictors of tumor response to neoadjuvant chemotherapy is of key importance, but none ...
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Clinicopathological features of ...
The common sites for metastases from breast cancer are lymph nodes, bone, lung, liver, and brain. Gastrointestinal (GI) metastasis is rarely found o ...
586.84 KB
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Vascular Access in Children
Establishment of stable vascular access is one of the essential and most challenging procedures in a pediatric hospital. Many clinical specialties p ...
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Antiplatelet and Anticoagulant ...
In treating peripheral arterial disease, a profound knowledge of antiplatelet and anticoagulative drug therapy is helpful to assure a positive clini ...
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Endovascular Management of Thor ...
The overall survival of patients with thoracic aortic aneurysm (TAA) has improved significantly in the past few years. Endovascular treatment, propo ...
352.67 KB
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Enhanced Antitumor Effect of Ti ...
Purpose We evaluated the effects of the combination of Tirapazamine (TPZ), activated preferentially under hypoxic conditions, and gelatin microspher ...
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Flow Changes after Endovascular ...
Endovascular treatment for a wide-neck anterior communicating artery (AcomA) aneurysm remains technically challenging. Stent-assisted embolization h ...
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LABA in patients with stage I C ...
Patients suffering from both sleep apnea-hypopnea syndrome (SAHS) and chronic obstructive pulmonary disease (COPD) have a more severe form of sleep a ...
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Heart-rate changes in asphyxic ...
Generally, it is assumed that heart-rhythm disorders during hypoxia result from the interplay between the autonomic nervous system (ANS) and the dire ...
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