Prognostic factor analysis of third-line chemotherapy i ...
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Prognostic factor analysis of t ...
Background Almost all patients with advanced gastric cancer will eventually develop progressive disease after first-line chemotherapy. However, the ...
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Does immigration play a role in ...
The observed increased risks of gastric cancer among first-generation immigrants compared to those in Swedes suggest the role of childhood environme ...
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Prognostic relevance of demogra ...
Background Although studies comparing the surgical treatment of gastric carcinoma in Japan and Western industrialized countries have revealed differ ...
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Caspase 8 and caspase 9 gene po ...
Background Caspase-8 (CASP8) and caspase-9 (CASP9) play crucial roles in regulating apoptosis, and their functional polymorphisms may alter cancer r ...
185.59 KB
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p53 codon 72 polymorphism in pa ...
Background The common p53 codon 72 polymorphism has been investigated as a risk factor for cancer in different populations; however, the results hav ...
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Phase II study of weekly paclit ...
Background Our previous phase I study provided evidence that weekly paclitaxel, cisplatin, and bolus 5-fluorouracil (weekly PCF) was effective and w ...
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Increased risk of tuberculosis ...
Background Gastrectomy for peptic ulcers and chemotherapy for malignancy are known risk factors for tuberculosis (TB). However, this relationship ha ...
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A phase II study of biweekly mi ...
Background Preclinical studies have shown that mitomycin C (MMC) acts synergistically with irinotecan (CPT- 11). In this phase II study, we evaluate ...
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IL-6 serum levels predict posto ...
Background Despite progress in surgical techniques and perioperative care, gastrectomy remains a procedure of significant morbidity. Several scoring ...
266.31 KB
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Human gastrin mRNA expression u ...
Background Helicobacter pylori-cytotoxin-associated protein A (CagA) and gastrin are believed to play an important role in gastric carcinogenesis, b ...
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Functional outcomes according t ...
Background In gastric cancer, various methods of gastric resection and reconstruction have been devised according to the location of the primary tum ...
248.31 KB
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A small interfering RNA targeti ...
Background Accumulating evidence suggests that the tumor suppressor gene Kruppel-like factor 6 (KLF6) and its dominant-negative splice form KLF6-SV1 ...
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Value of sentinel lymph node ma ...
Background Forty percent of patients with gastric cancer have unnecessarily extended lymph node dissections with higher rates of morbidity and morta ...
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Evaluation of modified Estimati ...
Background We recently modified our prediction scoring system ‘‘Estimation of Physiologic Ability and Surgical Stress’’ and have designated the curr ...
261.96 KB
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Bacteremia and endotoxemia afte ...
Background Because the invasive procedure of endoscopic submucosal dissection (ESD) entails a large mucosal defect which is left open, with extensiv ...
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Optimal indications of surgical ...
Background Decision-making for surgical palliation remains one of the most challenging clinical scenarios. We investigated the optimal indications f ...
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Survival benefit of bursectomy ...
Background Bursectomy is regarded as a standard surgical procedure during gastrectomy for serosa-positive gastric cancer in Japan. There is little e ...
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The delta-shaped anastomosis in ...
Background We developed a new method of intracorporeal gastroduodenostomy, the delta-shaped anastomosis, in which only endoscopic linear staplers ar ...
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First-line fluorouracil-based c ...
Background Treatment with an oral fluoropyrimidine plus cisplatin is widely used for advanced gastric cancer, but patients with severe peritoneal me ...
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Clinicopathological analysis fo ...
Background The prognosis for patients with stage Ib (second English edition of the Japanese classification of gastric carcinoma) gastric cancer is p ...
232.47 KB
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Decreased NKG2D expression on N ...
Background Although malignant diseases are known to be associated with immune suppression, the detailed mechanisms involved are still unknown. NKG2D ...
255.17 KB
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A multiple-center phase II stud ...
Background Docetaxel and oxaliplatin are active agents for advanced gastric cancer (GC). The combination of these two drugs in a triweekly schedule ...
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Frequent development of leptome ...
We detected 7 cases of leptomeningeal carcinomatosis in 126 patients with peritoneal dissemination of gastric cancer who received combined systemic ...
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Multicenter study of the long-t ...
Background Little information is available on the longterm outcomes of endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) in pati ...
255.95 KB
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Phase II trial of combined trea ...
Background To improve the poor prognosis in patients with stage IV (StIV) gastric cancer (GC), we conducted a multicenter phase II study of preopera ...
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