Defining and redefining the nephron progenitor populati ...
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Intradialytic hypotension
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Defining and redefining the nep ...
It has long been appreciated that the mammalian kidney arises via reciprocal interactions between an epithelial ureteric epithelium and the surround ...
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A 10-year-old boy with dark uri ...
Mitochondrial fatty acid â-oxidation (FAO) is essential for energy homeostasis in skeletal muscle under conditions that require simultaneous glucose ...
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Fetal environment, epigenetics, ...
The notion that some adult diseases may have their origins in utero has recently captured scientists’ attention. Some of these effects persist acros ...
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Abdominal pain in a female adol ...
Differential diagnosis of abdominal pain in a female teenager with autosomal dominant polycystic kidney disease (ADPKD) and insulin-dependent diabet ...
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Microvascular disease in childr ...
The incidence of type 1 diabetes (T1D) is increasing worldwide and is associated with a significant burden, mainly related to the development of vas ...
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aHUS caused by complement dysre ...
Atypical hemolytic uremic syndrome (aHUS) is a heterogeneous disease that is caused by defective complement regulation in over 50% of cases. Mutatio ...
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Patterning and early cell linea ...
Specification of the intermediate mesoderm and the epithelial derivatives that will make the mammalian kidney depends on the concerted action of man ...
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TRPC channel modulation in podo ...
Glomerular kidney disease is a major healthcare burden and considered to represent a sum of disorders that evade a refined and effective treatment. ...
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New therapies in steroid-sensit ...
Although many children with idiopathic nephrotic syndrome (INS) respond initially to steroid therapy, repeated courses for patients with relapses of ...
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Dent’s disease: clinical featur ...
Dent’s disease is an X-linked recessive renal tubulopathy characterized by low-molecular-weight proteinuria (LMWP), hypercalciuria, nephrocalcinosis ...
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Abdominal pain in a female adol ...
A 16-year-old white female presented to the emergency department (ED) with complaints of multiple episodes of vomiting, colicky left flank, and lowe ...
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Genetics of congenital anomalie ...
Congenital anomalies of the kidney and urinary tract (CAKUT) occur in 1 in 500 births and are a major cause of morbidity in children. Notably, CAKUT ...
دانلود 1
999.96 KB
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Cystinosis: practical tools for ...
Cystinosis is the major cause of inherited Fanconi syndrome, and should be suspected in young children with failure to thrive and signs of renal pro ...
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Biomarkers of acute kidney inju ...
Acute kidney injury (AKI) in children is associated with increased mortality and prolonged length of hospital stay and may also be associated with l ...
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Renal amyloidosis in children
Renal amyloidosis is a detrimental disease caused by the deposition of amyloid fibrils. A child with renal amyloidosis may present with proteinuria ...
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Ciliopathies: an expanding dise ...
Ciliopathies comprise a group of disorders associated with genetic mutations encoding defective proteins, which result in either abnormal formation ...
842.60 KB
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Intradialytic hypotension
Intradialytic hypotension (IDH) is common in children during conventional, 4 hour haemodialysis (HD) sessions. The declining blood pressure (BP) was ...
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Diagnosis and management of chi ...
A number of syndromic disorders have renal cysts as a component of their phenotypes. These disorders can generally be distinguished from autosomal d ...
دانلود 1
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Management of toxic ingestions ...
Although rare, renal replacement therapy (RRT) for the treatment of the metabolic, respiratory and hemodynamic complications of intoxications may be ...
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PPARم and chronic kidney diseas ...
Peroxisome proliferator-activated receptor-م (PPARم) agonists, exemplified by the thiazolidinediones (TZDs), have been used extensively for their be ...
111.15 KB
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Parathyroid hormone and growth ...
Growth failure is common in children with chronic kidney disease, and successful treatment is a major challenge in the management of these children. ...
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Consequences and therapy of the ...
Metabolic acidosis is common in patients with chronic kidney disease (CKD), particularly once the glomerular filtration rate (GFR) falls below 25 ml ...
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Role of fibroblast growth facto ...
Fibroblast growth factor receptors (Fgfrs) are expressed throughout the developing kidney. Several early studies have shown that exogenous fibroblas ...
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Nocturnal enuresis—theoretic ba ...
Nocturnal polyuria, nocturnal detrusor overactivity and high arousal thresholds are central in the pathogenesis of enuresis. An underlying mechanism ...
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Heat shock proteins in chronic ...
Heat shock proteins (HSP) form a heterogenous, evolutionarily conserved group of molecules with high sequence homology. They mainly act as intracell ...
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